Chronic total occlusion(CTO)of the coronary artery is a common occurrence among patients un-dergoing percutaneous coronary intervention(PCI),a procedure known for its difficulty and associated risks.However,the precise clinical endpoint benefit of CTO-PCI remains unclear.In this review,we aim to provide a comprehensive summary of recent randomized controlled clinical trials(RCTs)and observational studies pertaining to CTO-PCI.Additionally,we introduced the latest PCI devices and management strategies developed in recent years.By consolidating existing evidence and advancements,this review seeks to offer a new theoretical and prac-tical foundation for enhancing CTO-PCI procedures and outcomes.
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