Objective:To explore the effectiveness and safety of X-ray guided left atrial appendage occlusion combined with catheter ablation.Methods:Patients with non-valvular atrial fibrillation who underwent catheter ablation and were admitted to the 7th People's Hospital of Zhengzhou from March 2017 to April 2022 were includ-ed.These patients were divided into the transesophageal echocardiography combined with X-ray group(TEE group,n=73)and the X-ray group(DSA group,n=73)using propensity score matching.Followed up for 12 months,perioperative and follow-up data were compared between the two groups,the effectiveness,safety,and economic benefits of using X-ray guidance alone for left atrial appendage occlusion combined with catheter ablation were evaluated.Results:Patients in both groups successfully completed catheter ablation and left atrial appendage occlusion.The incidence of small pericardial effusion(20.5％vs 8.2％),hospitalization duration[(10.5±2.7)d vs(9.3±2.6)d],and expenses[¥(156 517.7±13 271.2)vs ¥(146 028.1±12 481.1)]in the DSA group were significantly lower than those in the TEE group(all P＜0.05).There was no statistically significant difference in the incidence of endpoint events during the followup period between the two groups.Conclusion:For left atrial ap-pendage occlusion combined with catheter ablation,the effectiveness and safety of X-ray guidance alone are not in-ferior to that of X-ray combined with transesophageal echocardiography guidance,and it has certain advantages in reducing hospitalization costs and length of stay.
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