The efficacy of circumferential pulmonary vein combined with additional ablation in reducing recurrence of atrial fibrillation after radiofrequency ablation:a meta-analysis
Objective:To investigate whether circumferential pulmonary vein isolation(CPVI)combined with additional ablation(mitral isthmus,tricuspid isthmus,superior vena cava,left atrial roof,left atrial posterior wall,the vein of marshall,complex fractionated atrial electrograms,ganglionated plexi)reduces the recurrence rate of atrial fibrillation(AF)compared with CPVI alone.Methods:A literature search was conducted using the databases CNKI,WanFang,VIP,CBM,PubMed,Embase,Cochrane Library.Randomized controlled studies that met the standards in the past ten years were screened out,and the relevant literature contents were meta-ana-lyzed by Stata software.The content about comparing CPVI alone with CPVI combined with the additional abla-tion strategies in the recurrence of AF was summarized.Results:A total of 21 papers were included.Meta-analy-sis showed that no significant difference between CPVI alone and CPVI combined ablation strategies in reducing AF recurrence.Subgroup analysis based on additional ablation site,AF type,left atrial diameter,AF diagnosis time,and outcome indicators showed that only in the small left atrial diameter subgroup,CPVI combined with ad-ditional ablation further reduced the recurrence rate of AF(OR=0.68,95％CI:0.47-0.98,P=0.040),which was not found in other subgroups.Conclusion:The ablation strategy of CPVI combined with additional sites does not reduce the recurrence rate of AF compared with CPVI alone.
维普
万方数据
