临床心血管病杂志2024,Vol.40Issue(7) :570-573.DOI:10.13201/j.issn.1001-1439.2024.07.012

高龄患者无导线起搏器植入临床疗效观察

Clinical observation of leadless pacemaker implantation in elderly patients

乔瀚博 方潘慧 陶元 乔增勇 邓海燕
临床心血管病杂志2024,Vol.40Issue(7) :570-573.DOI:10.13201/j.issn.1001-1439.2024.07.012

高龄患者无导线起搏器植入临床疗效观察

Clinical observation of leadless pacemaker implantation in elderly patients

乔瀚博 1方潘慧 2陶元 3乔增勇 3邓海燕3
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作者信息

  • 1. 上海市普陀区利群医院心内科(上海,200333)
  • 2. 上海市奉贤区中心医院全科规培基地
  • 3. 上海市奉贤区中心医院心内科
  • 折叠

摘要

目的:初步探讨高龄患者无导线起搏器植入后电学参数的稳定性,分析无导线起搏器在临床应用中的有效性及安全性.方法:本研究为回顾性、观察性研究.选取2021年8月-2023年2月于上海市奉贤区中心医院和上海市普陀区利群医院接受单、双腔无导线起搏器植入的52例年龄≥70岁患者.收集患者的基本特征以及围术期相关信息.术后随访程控参数(感知、阈值、阻抗)、超声心动图、B型利钠肽(BNP)、肌酐.收集并发症及严重不良事件发生情况.结果:52例患者均完成起搏器植入,成功率为100%.术中阈值(0.53±0.24)V/0.24 ms,感知(11.67±4.65)mV,阻抗(831.88±194.82)Ω,手术时间(39.41±19.54)min,住院时间(9.25±3.72)d.围手术期均未发生空气血栓栓塞、心脏穿孔、心包填塞等严重并发症,均未发生起搏器脱落或移位.术后1个月超声心动图显示三尖瓣功能无明显变化.术后6个月随访时,阈值(0.48±0.10)V/0.24 ms,感知(13.38±3.89)mV,阻抗(716.88±141.23)Ω,心室起搏比例为54.1%.与术中相比,术后6个月起搏感知及阈值无显著改变,阻抗则呈下降趋势(P<0.05).结论:对于高龄患者,植入无导线起搏器术中与术后电学参数稳定,并发症发生率低,在临床应用中安全有效.

Abstract

Objective:To preliminarily explore the stability of electrical parameters after leadless pacemaker implantation in elderly patients and evaluate the efficacy and safety of leadless pacemakers in clinical application.Methods:This study was a retrospective and observational research.Fifty-two patients aged≥70 years who re-ceived single or dual chamber leadless pacemaker implantation in Shanghai Fengxian District Central Hospital and Shanghai Putuo District Liqun Hospital from August 2021 to February 2023 were selected.The basic characteris-tics and perioperative data were collected.The parameters of leadless pacemaker(R-wave,threshold,imped-ance),echocardiography,brain natriuretic peptide(BNP),and creatinine were followed up after implantation.The complications and serious adverse events were also recorded.Results:Fifty-two patients completed pacemaker implantation with a success rate of 100%.The intraoperative mean ventricular pacing threshold was(0.53±0.24)V at 0.24 ms,the leadless pacemaker R-wave was(11.67±4.65)mV,impedance was(831.88±194.82)Ω,op-eration time was(39.41±19.54)min,and hospital stay was(9.25±3.72)d.There was no perioperative air thromboembolism,cardiac perforation,pericardial tamponade,pacemaker falling off,or shifts.The tricuspid valve function showed no significant change under echocardiography one month after implantation.The electrical parameters 6 months after implantation:mean ventricular pacing threshold was(0.48±0.10)V at 0.24 ms,lead-less pacemaker R-wave was(13.38±3.89)mV,impedance was(716.88±141.23)Ω,and ventricular pacing was 54.1%.Compared with intraoperative values,there was no significant change in the leadless pacemaker R-wave or threshold,while the impedance showed a decreasing trend(P<0.05).Conclusion:For elderly patients,leadless pacemaker implantation has stable electrical parameters during and after the implantation,with the low incidence of complications.It is safe and effective in clinical applications.

关键词

无导线起搏器/电学参数/高龄/并发症

Key words

leadless pacemaker/electrical parameters/elderly/complications

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基金项目

上海市科学技术委员会基金(19JC1415704)

出版年

2024
临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

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影响因子:0.653
ISSN:1001-1439
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