Objective:To explore the clinical efficacy of cardiac contractility modulation(CCM)in patients with chronic heart failure.Methods:This study retrospectively analyzed the clinical data of eight patients with chronic heart failure who underwent CCM implantation in the Department of Cardiology,The First Affiliated Hos-pital of Soochow University from May 2022 to May 2023.The differences in left ventricular ejection fraction(LVEF),left ventricular end-diastolic dimension(LVEDD),left atrium diameter(LAD),pulmonary artery sys-tolic pressure(PASP),and NYHA functional classification before and after 6 months of treatment were compared to observe changes in clinical symptoms.Results:Compared to pre-implantation,all observed indicators of pa-tients improved six months after CCM implantation:LVEF increased from(25.6±4.7)％to(35.6±5.6)％(t=-7.5,P＜0.05),LVEDD decreased from(70.0±2.4)mm to(65.1±3.9)mm(t=4.2,P＜0.05),LAD decreased from(53.0±6.2)mm to(48.4±7.0)mm(t=2.1,P＞0.05),and PASP decreased from[27.0(19.5,37.8)]mmHg to[23.5(19.8,26.8)]mmHg(Z=-1.7,P＞0.05).All patients reached NYHA func-tional classification Ⅱ.Symptoms such as chest tightness and dyspnea showed significant improvement.Conclu-sion:CCM effectively improves the left ventricular ejection fraction in patients with chronic heart failure and reverses ven-tricular remodeling.
维普
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