左心室辅助装置植入同期干预主动脉瓣反流的现状与研究进展
Current status and research progress of left ventricular assist device implantation with concomitant intervention of aortic regurgitation
王志华 1胡俊龙 1程兆云1
作者信息
- 1. 郑州大学华中阜外医院心外科(郑州,451464)
- 折叠
摘要
主动脉瓣反流(aortic regurgitation,AR)是终末期心力衰竭(心衰)患者接受左心室辅助装置(left ventricular assist device,LVAD)植入前评估和植入后管理的重要考虑因素.AR可在LVAD植入前即存在,也可在LVAD支持期间出现.AR通常是一种进行性疾病,可导致LVAD疗效降低和再发心衰症状.越来越多的研究显示,严重的AR会导致LVAD患者的血流动力学恶化、再入院率和死亡率增加.本文就接受LVAD植入的终末期心衰患者合并AR的发生率、病理生理学、危险因素、手术时机及方式、手术预后及指南、术后预防及管理的现状与研究进展进行综述.
Abstract
Aortic regurgitation(AR)is an important consideration in the pre-implantation evaluation and post-implantation management of patients with end-stage heart failure undergoing left ventricular assist device(LVAD).AR can be pre-existing prior to LVAD implantation or present during LVAD support.AR is usually a progressive disease that can lead to reduced LVAD efficacy and recurrent heart failure symptoms.A growing num-ber of studies have shown that significant AR leads to hemodynamic deterioration,increased readmission rates and mortality in patients with LVAD.This review updated the progress in the incidence,pathophysiology,risk fac-tors,timing and method of surgery,surgical prognosis and guidelines,and postoperative prevention and manage-ment of comorbid AR in patients with end-stage heart failure who underwent LVAD implantation.
关键词
心力衰竭/左心室辅助装置/主动脉瓣反流/手术干预Key words
heart failure/left ventricular assist device/aortic regurgitation/surgical intervention引用本文复制引用
基金项目
河南省重点研发专项(221111310300)
河南省医学科技攻关计划项目(LHGJ20220111)
河南省医学科技攻关计划项目(SBGJ202101005)
出版年
2024
NETL
NSTL
万方数据