Aortic regurgitation(AR)is an important consideration in the pre-implantation evaluation and post-implantation management of patients with end-stage heart failure undergoing left ventricular assist device(LVAD).AR can be pre-existing prior to LVAD implantation or present during LVAD support.AR is usually a progressive disease that can lead to reduced LVAD efficacy and recurrent heart failure symptoms.A growing num-ber of studies have shown that significant AR leads to hemodynamic deterioration,increased readmission rates and mortality in patients with LVAD.This review updated the progress in the incidence,pathophysiology,risk fac-tors,timing and method of surgery,surgical prognosis and guidelines,and postoperative prevention and manage-ment of comorbid AR in patients with end-stage heart failure who underwent LVAD implantation.
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