Impact of low density lipoprotein cholesterol/high density lipoprotein cholesterol ratio and monocyte/lymphocyte ratio on cardiovascular events in patients with ischemic myocardial fibrosis
Objective:To investigate the value of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio(LDL/HDL)and monocyte/lymphocyte ratio(MLR)in predicting major adverse cardiovascular e-vents in patients with ischemic myocardial fibrosis(IMF).Methods:A total of 159 patients with IMF were select-ed as the IMF group and 150 patients with non-IMF as the control group.The clinical data,serum LDL/HDL and MLR levels of all patients were recorded.The incidence of major adverse cardiovascular events(MACE)in all pa-tients was collected during 1-year follow-up,and the related factors of MACE were evaluated by multivariate lo-gistic regression analysis.Results:The serum levels of LDL/HDL and MLR in IMF group were significantly higher than those in control group.Compared with IMF patients without MACE,serum levels of LDL/HDL and MLR were significantly higher in patients with MACE events.Multivariate logistic regression analysis showed that LDL/HDL and MLR were independent factors in the occurrence of MACE.Conclusion:Serum LDL/HDL and MLR are inde-pendent risk factors for MACE in IMF patients.
low density lipoprotein cholesterol/high density lipoprotein cholesterol ratiomonocyte/lympho-cyte ratioischemic myocardial fibrosismajor adverse cardiovascular event