低密度脂蛋白胆固醇/高密度脂蛋白胆固醇比值和单核细胞/淋巴细胞比值对缺血性心肌纤维化患者心血管事件的影响
Impact of low density lipoprotein cholesterol/high density lipoprotein cholesterol ratio and monocyte/lymphocyte ratio on cardiovascular events in patients with ischemic myocardial fibrosis
易胜利 1邓啊味 2邓玮3
作者信息
- 1. 重庆医科大学附属第二医院全科医学科 重庆市老年医学临床研究中心(重庆,400010);重庆市开州区人民医院全科医学科
- 2. 重庆医科大学附属第二医院呼吸内科
- 3. 重庆医科大学附属第二医院全科医学科 重庆市老年医学临床研究中心(重庆,400010)
- 折叠
摘要
目的:探讨低密度脂蛋白胆固醇/高密度脂蛋白胆固醇比值(LDL/HDL)、单核细胞/淋巴细胞比值(MLR)对缺血性心肌纤维化(IMF)患者主要不良心血管事件(MACE)的预测价值.方法:连续入选159例IMF患者作为IMF组,150例非IMF患者作为对照组(non-IMF组),记录所有患者临床资料、血清LDL/HDL、MLR水平等.随访1年,收集所有患者MACE发生情况,多因素logistic回归分析评估MACE的相关因素.结果:IMF组患者血清LDL/HDL、MLR水平明显高于对照组.与未发生MACE的IMF患者相比,发生MACE的患者血清LDL/HDL、MLR水平明显升高.多因素logistic回归分析结果显示,LDL/HDL、MLR是发生MACE的独立影响因素.结论:血清LDL/HDL、MLR是IMF患者发生MACE的独立危险因素.
Abstract
Objective:To investigate the value of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio(LDL/HDL)and monocyte/lymphocyte ratio(MLR)in predicting major adverse cardiovascular e-vents in patients with ischemic myocardial fibrosis(IMF).Methods:A total of 159 patients with IMF were select-ed as the IMF group and 150 patients with non-IMF as the control group.The clinical data,serum LDL/HDL and MLR levels of all patients were recorded.The incidence of major adverse cardiovascular events(MACE)in all pa-tients was collected during 1-year follow-up,and the related factors of MACE were evaluated by multivariate lo-gistic regression analysis.Results:The serum levels of LDL/HDL and MLR in IMF group were significantly higher than those in control group.Compared with IMF patients without MACE,serum levels of LDL/HDL and MLR were significantly higher in patients with MACE events.Multivariate logistic regression analysis showed that LDL/HDL and MLR were independent factors in the occurrence of MACE.Conclusion:Serum LDL/HDL and MLR are inde-pendent risk factors for MACE in IMF patients.
关键词
低密度脂蛋白胆固醇/高密度脂蛋白胆固醇比值/单核细胞/淋巴细胞比值/缺血性心肌纤维化/主要不良心血管事件Key words
low density lipoprotein cholesterol/high density lipoprotein cholesterol ratio/monocyte/lympho-cyte ratio/ischemic myocardial fibrosis/major adverse cardiovascular event引用本文复制引用
出版年
2024
NETL
NSTL
万方数据