首页|经导管主动脉瓣置换术冠状动脉阻塞风险预防的单中心研究

经导管主动脉瓣置换术冠状动脉阻塞风险预防的单中心研究

A single-center study of risk prevention of coronary artery occlusion after transcatheter aortic valve replacement

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目的:探讨经导管主动脉瓣置换术(transcatheter aortic valve replacement,TAVR)冠状动脉(冠脉)阻塞风险的有效预防策略.方法:收集2016年1月-2024年1月于河北医科大学第二医院行TAVR患者的围手术期资料,回顾性分析TAVR术后患者冠脉阻塞事件的发生情况.结果:共行TAVR 385例,其中经外周入路321例,经心尖入路64例;冠脉高风险72例,术中行冠脉保护26例("烟囱"支架2例、冠脉开口支架开窗20例、冠脉保护性导丝或支架预置入4例),应用冠脉风险较低的J-Valve瓣膜17例,其余病例经进一步风险评估初步排除冠脉风险,未予冠脉保护或行相应处理;术后冠脉阻塞发生1例(0.3%).结论:冠脉阻塞是经导管主动脉瓣置换术后极为严重的并发症,虽整体发生水平不高,但致死性极强.对于冠脉高风险TAVR病例,预防重于补救,术前详尽研判、术中充分保护意义重大.围手术期内方法合理、策略得当可有效降低TAVR相关冠脉阻塞事件的发生,提高整体手术的成功率.
Objective:To explore the effective prevention strategy of transcatheter aortic valve replacement(TAVR)and summarize the relevant experience.Methods:The perioperative data of TAVR patients in the Sec-ond Hospital of Hebei Medical University from 2016 to 2024 were collected,and the occurrence of coronary artery occlusion events in patients after TAVR was retrospectively analyzed.Results:A total of 385 cases of TAVR were treated,including 321 cases via peripheral approach and 64 cases via apical approach.There were 72 high-risk ca-ses with coronary artery,26 cases received coronary artery protection during the operation(2 cases with"chimney"stent,20 cases with coronary opening stent window opening,and 4 cases with coronary protective guide wire or stent prepositioning),17 cases received J-Valve valve with low coronary risk,and the remaining cases were pre-liminatively excluded by further risk assessment without coronary artery protection or corresponding treatment.Postoperative coronary artery obstruction occurred in 1 case,and the incidence of coronary artery obstruction was 0.3%.Conclusion:Coronary artery occlusion is a very serious complication after transcatheter aortic valve re-placement.Although the overall incidence is not high,it is extremely fatal.For high-risk coronary TAVR cases,prevention is more important than remedy,and detailed preoperative investigation and adequate protection during operation are of great significance.In the perioperative period,reasonable methods and proper strategies can effec-tively reduce the occurrence of TAVR-related coronary artery obstruction events and improve the overall success rate of surgery.

coronary artery obstructiontranscatheter aortic valve replacementprevent

张航、王华君、石凤梧、刘苏、马千里、安景辉

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河北医科大学第二医院心脏外科(石家庄,050000)

冠状动脉阻塞 经导管主动脉瓣置换术 预防

2023年度河北省医学科学研究课题

23230440

2024

临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

CSTPCD
影响因子:0.653
ISSN:1001-1439
年,卷(期):2024.40(8)
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