首页|Stanford A型主动脉夹层患者孙氏手术后早期截瘫原因分析

Stanford A型主动脉夹层患者孙氏手术后早期截瘫原因分析

Causes of early paraplegia following Sun's procedure in patients with stanford type A aortic dissection

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目的:回顾性分析Stanford A型主动脉夹层患者接受孙氏手术后出现早期截瘫的围术期危险因素.方法:收集2021年1月-12月因Stanford A型主动脉夹层收治于华中科技大学同济医学院附属同济医院心脏大血管外科并行孙氏手术的178例患者的临床资料,其中男性140例、女性38例,平均年龄为(51.5±10.7)岁,术后截瘫患者7例(3.9%).统计分析截瘫组与非截瘫组患者围术期临床数据.测量并记录患者术后CTA影像肋间动脉开口位置以及开放程度,探究术后截瘫的原因以及危险因素.结果:非截瘫组和截瘫组患者性别、身高、体重、心血管病史、主动脉阻断时间、中低温停循环时间以及肛温差异均无统计学意义.两组患者术前低血压事件与年龄均差异有统计学意义(均P<0.05),截瘫组患者CTA影像Th7~Th11肋间动脉的起始处与肺动脉分叉水平主动脉CT值比值(Hounsfield ratio,HUR)显著低于非截瘫组患者(P<0.05).多因素logistic回归分析提示,术前低血压事件(OR=33.80,P<0.05)、支架覆盖的肋间动脉数量≥8支(OR=35.00,P<0.05)与假腔供血肋间动脉数量≥10支(OR=36.71,P<0.05)均增加术后截瘫风险.结论:Stanford A型主动脉夹层术前低血压事件、支架覆盖肋间动脉≥8支和假腔供血肋间动脉≥10支是术后截瘫的危险因素;HUR有望对残余肋间动脉供血状况进行评估,有一定的临床指导价值.
Objective:To retrospectively analyse perioperative risk factors of early paraplegia in patients with Stanford type A aortic dissection undergoing Sun's procedure.Methods:All patients who underwent Sun's proce-dure from January to December 2021 in Tongji Hospital were retrospectively analysed.There were 178 patients with 140 males and 38 females at a mean age of(51.5±10.7)years,and 7 patients(3.9%)of them developed postoperative paraplegia.We performed a statistical analysis of perioperative clinical data between the paraplegia and non-paraplegia groups.The locations of the Th7-Th12 intercostal arteries'origin and blood supply were also recorded to investigate the cause of early paraplegia.Results:Among the 178 patients,there were no statistical differences in gender,height,weight,history,aortic crossclamping time,moderate hypothermic circulatory ar-rest time(antegrade cerebral perfusion)and anal temperature between the paraplegia group and non-paraplegia group.Preoperative hypotension events and age had statistically significant differences between the two groups(both P<0.05).Hounsfield ratio(HUR)from Th7 to Th11 showed statistical differences between the two groups(P<0.05).Logistic regression analysis suggested that preoperative hypotension(OR=33.80,P<0.05),the number of stent-covered intercostal arteries ≥8(OR=35.00,P<0.05),and the number of intercostal arter-ies from false lumen ≥10(OR=36.71,P<0.05)increased the risk of postoperative paraplegia.Conclusion:Pre-operative hypotension,covered intercostal artery ≥8,and intercostal arteries from false lumen ≥10 may be risk factors for postoperative paraplegia in Stanford type A aortic dissection.HUR has a certain guiding significance in evaluating the blood supply of the residual intercostal artery.

Stanford type A aortic dissectionparaplegiaspinal cord ischemiaHounsfield ratio

陈司奇、魏翔、陈太强

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华中科技大学同济医学院附属同济医院心脏大血管外科(武汉,430030)

Stanford A型主动脉夹层 截瘫 脊髓缺血 亨氏单位比值

2024

临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

CSTPCD
影响因子:0.653
ISSN:1001-1439
年,卷(期):2024.40(9)