首页|冲击波冠状动脉球囊在冠状动脉严重钙化病变介入治疗中的应用

冲击波冠状动脉球囊在冠状动脉严重钙化病变介入治疗中的应用

The application of shockwave balloon in percutaneous coronary intervention for severe coronary artery calcification

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目的:观察新型冲击波球囊碎石技术在冠状动脉(冠脉)严重钙化病变中的治疗效果.方法:根据冠脉造影结果以及腔内影像学指导,将25例患者分为冲击波组(15例)和对照组(10例).其中,冲击波组12例采用光学相干断层成像(optical coherence tomography,OCT)检查,3 例采用血管内超声(intravascular ultrasound,IVUS)检查;对照组6例行OCT检查,4例行IVUS检查.比较两组患者术中使用耗材情况、手术曝光时间、斑块负荷、最小管腔直径、最小管腔面积、支架内最小管腔面积及支架膨胀率,并记录术后和半年随访期间发生的主要心血管不良事件.结果:冲击波组术中使用耗材数量明显减少,曝光时间明显缩短[(120.34±7.05)min vs(80.66±6.19)min,P<0.05].两组患者术后的斑块负荷、最小管腔直径和最小管腔面积均较术前明显改善(均P<0.05).与对照组比较,冲击波组术后支架内最小管腔面积[(9.23±1.37)mm2 vs(11.89±3.25)mm2,P<0.05]和支架膨胀率[(78.31±3.55)%vs(89.22±2.65)%,P<0.05]改善更为明显.所有患者术后以及半年随访期间均未发生主要心血管不良事件.结论:冲击波球囊导管技术在冠脉严重钙化病变中应用是安全有效的.
Objective:To evaluate the therapeutic effect of a new type of shockwave lithotripsy in the treat-ment of severe coronary calcification.Methods:Based on the results of coronary angiography and guidance of int-racavitary imaging,25 patients were divided into the shockwave group(n=15)and control group(n=10).In the shockwave group,OCT was performed in 12 cases and IVUS in 3 cases.In the control group,OCT was per-formed in 6 cases and IVUS in 4 cases.The use of consumables during the operation,surgical exposure time,plaque burden,minimal lumen diameter,minimal lumen area,minimal lumen area inside the stent,and stent ex-pansion rate were compared between the two groups.Major cardiovascular adverse events were recorded after sur-gery and during the 6-month follow-up.Results:In the shockwave group,the amount of consumables use during operation was significantly reduced and the exposure time was significantly shortened[(120.34±7.05)min vs(80.66±6.19)min,P<0.05].The plaque burden,minimum lumen diameter,and minimum lumen area after surgery were significantly improved compared to those before operation in both groups(all P<0.05).Compared with the control group,the minimum lumen area in the stent[(9.23±1.37)mm2 vs(11.89±3.25)mm2,P<0.05]and stent expansion rate[(78.31±3.55)%vs(89.22±2.65)%,P<0.05]improved more significantly in the shockwave group.There was no major cardiovascular adverse events occurred in all patients after surgery and during the 6-month follow-up.Conclusion:It is safe and effective to apply the technique of shockwave balloon catheter in coronary artery severe calcification.

coronary calcificationshockwave balloonendoluminal imaging

张志岗、雷新宇、孙宇飞、黄阳霞、闫超、魏首栋

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山西医科大学附属心血管病医院心内科(太原,030024)

冠状动脉钙化 冲击波球囊导管 腔内影像学

2024

临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

CSTPCD
影响因子:0.653
ISSN:1001-1439
年,卷(期):2024.40(9)