重度慢性血栓栓塞性肺动脉高压的治疗策略
Treatment strategies for patients with severe chronic thromboembolic pulmonary hypertension
曾怡 1何田 2张静3
作者信息
- 1. 电子科技大学医学院(成都,610054);四川省医学科学院·四川省人民医院呼吸与危重症医学科
- 2. 四川省医学科学院·四川省人民医院呼吸与危重症医学科;成都中医药大学
- 3. 四川省医学科学院·四川省人民医院呼吸与危重症医学科
- 折叠
摘要
慢性血栓栓塞性肺动脉高压(CTEPH)是一种致命性疾病,由于诊断延迟、诊断不充分等,大多数患者就诊时已达到重度肺动脉高压水平.对于这些重度肺动脉高压患者,单一治疗效果不佳,可选择将肺动脉内膜剥脱术(PEA)与球囊肺动脉成形术(BPA)、靶向药物相结合,以降低手术风险,或解决残余肺动脉高压.多种药物联合或BPA与药物组合为无法手术的CTEPH患者提供了新的治疗选择.本文旨在为重度CTEPH-患者的治疗,尤其是联合治疗方案的选择提供参考.
Abstract
Chronic thromboembolic pulmonary hypertension(CTEPH)is a fatal disease.Due to delayed diag-nosis or inadequate diagnosis,most patients have reached the level of severe pulmonary hypertension at the time of diagnosis.For patients with severe pulmonary hypertension,a single treatment is not effective.Pulmonary endar-terectomy(PEA)can be combined with balloon pulmonary angioplasty(BPA)or targeted drugs to reduce the risk of surgery or solve residual pulmonary hypertension.Multiple drug combinations or BPA in combination with drugs provide new treatment options for patients with inoperable CTEPH.This article aims to provide a reference for treating patients with severe CTEPH,especially the choice of combined treatment options.
关键词
肺动脉高压,血栓栓塞性,慢性/肺动脉内膜剥脱术/球囊肺动脉成形术Key words
chronic thromboembolic pulmonary hypertension/pulmonary endarterectomy/balloon pulmona-ry angioplasty引用本文复制引用
基金项目
四川省医学科研课题计划(S19011)
四川省科技计划项目(2022YFS0107)
出版年
2024
NETL
NSTL
万方数据