Chronic thromboembolic pulmonary hypertension(CTEPH)is a fatal disease.Due to delayed diag-nosis or inadequate diagnosis,most patients have reached the level of severe pulmonary hypertension at the time of diagnosis.For patients with severe pulmonary hypertension,a single treatment is not effective.Pulmonary endar-terectomy(PEA)can be combined with balloon pulmonary angioplasty(BPA)or targeted drugs to reduce the risk of surgery or solve residual pulmonary hypertension.Multiple drug combinations or BPA in combination with drugs provide new treatment options for patients with inoperable CTEPH.This article aims to provide a reference for treating patients with severe CTEPH,especially the choice of combined treatment options.
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