首页|药物涂层球囊治疗冠状动脉病变合并糖尿病的研究进展

药物涂层球囊治疗冠状动脉病变合并糖尿病的研究进展

Drug-coated balloons for the treatment of coronary artery lesions combined with diabetes mellitus

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糖尿病是冠状动脉(冠脉)疾病和心血管事件的主要危险因素,其患者复杂的血管情况也是经皮冠脉介入治疗(PCI)所面临的主要挑战之一.尽管药物洗脱支架的使用降低了糖尿病患者的冠脉再狭窄率,但与非糖尿病患者相比,糖尿病患者支架置入术后发生主要不良心血管事件的风险仍然增加.为了进一步降低支架术后并发症,在无植入理念的驱动下,药物涂层球囊(DCB)作为冠脉介入治疗新手段应运而生,为合并糖尿病的冠脉病变介入治疗提供了新策略.本综述总结了近年来DCB用于治疗糖尿病患者冠脉病变的临床研究,以探究DCB治疗冠脉血管病变合并糖尿病的疗效和安全性.
Diabetes mellitus is a major risk factor for coronary artery disease and cardiovascular events,and the complex vascular profile of its patients is one of the major challenges facing PCI.Although the use of drug-elu-ting stents has reduced the rate of coronary restenosis in diabetic patients,there is still an increased risk of MACE after stent placement in diabetic patients compared to non-diabetic patients.To further minimize post-stenting complications,drug-coated balloon(DCB)has emerged as a new means of coronary intervention driven by the no-implantation concept,which provides a new strategy for interventional treatment of coronary lesions with comor-bid diabetes.This review summarizes the clinical studies on the use of DCB for the treatment of coronary artery le-sions in diabetic patients in recent years,in order to investigate the efficacy and safety of DCB for the treatment of coronary artery vasculopathy combined with diabetes mellitus.

diabetescoronary heart diseasedrug-coated balloonpercutaneous coronary intervention

崔璐、林立志、张亚茹、朱浩然、申程、王明皓、赵馨宇、曹勇

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济宁医学院临床医学院(山东济宁,272000)

济宁市冠状动脉介入精准治疗重点实验室

济宁医学院附属医院心内科冠心病二病区

糖尿病 冠心病 药物涂层球囊 经皮冠状动脉介入治疗

济宁市重点研发计划项目济宁医学院附属医院主诊医师团队专项临床研究计划项目

2022YXNS022ZZTD-2022-002

2024

临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

CSTPCD
影响因子:0.653
ISSN:1001-1439
年,卷(期):2024.40(10)