药物涂层球囊治疗冠状动脉病变合并糖尿病的研究进展
Drug-coated balloons for the treatment of coronary artery lesions combined with diabetes mellitus
崔璐 1林立志 1张亚茹 1朱浩然 1申程 2王明皓 2赵馨宇 1曹勇2
作者信息
- 1. 济宁医学院临床医学院(山东济宁,272000);济宁市冠状动脉介入精准治疗重点实验室
- 2. 济宁市冠状动脉介入精准治疗重点实验室;济宁医学院附属医院心内科冠心病二病区
- 折叠
摘要
糖尿病是冠状动脉(冠脉)疾病和心血管事件的主要危险因素,其患者复杂的血管情况也是经皮冠脉介入治疗(PCI)所面临的主要挑战之一.尽管药物洗脱支架的使用降低了糖尿病患者的冠脉再狭窄率,但与非糖尿病患者相比,糖尿病患者支架置入术后发生主要不良心血管事件的风险仍然增加.为了进一步降低支架术后并发症,在无植入理念的驱动下,药物涂层球囊(DCB)作为冠脉介入治疗新手段应运而生,为合并糖尿病的冠脉病变介入治疗提供了新策略.本综述总结了近年来DCB用于治疗糖尿病患者冠脉病变的临床研究,以探究DCB治疗冠脉血管病变合并糖尿病的疗效和安全性.
Abstract
Diabetes mellitus is a major risk factor for coronary artery disease and cardiovascular events,and the complex vascular profile of its patients is one of the major challenges facing PCI.Although the use of drug-elu-ting stents has reduced the rate of coronary restenosis in diabetic patients,there is still an increased risk of MACE after stent placement in diabetic patients compared to non-diabetic patients.To further minimize post-stenting complications,drug-coated balloon(DCB)has emerged as a new means of coronary intervention driven by the no-implantation concept,which provides a new strategy for interventional treatment of coronary lesions with comor-bid diabetes.This review summarizes the clinical studies on the use of DCB for the treatment of coronary artery le-sions in diabetic patients in recent years,in order to investigate the efficacy and safety of DCB for the treatment of coronary artery vasculopathy combined with diabetes mellitus.
关键词
糖尿病/冠心病/药物涂层球囊/经皮冠状动脉介入治疗Key words
diabetes/coronary heart disease/drug-coated balloon/percutaneous coronary intervention引用本文复制引用
基金项目
济宁市重点研发计划项目(2022YXNS022)
济宁医学院附属医院主诊医师团队专项临床研究计划项目(ZZTD-2022-002)
出版年
2024
NETL
NSTL
万方数据