Objective:To explore the role of cardiopulmonary bypass(CPB)in transcatheter aortic valve re-placement(TAVR).The application of TAVR+percutaneous coronary intervention(PCI),and the relevant ex-perience were summarized.Methods:Clinical data of patients undergoing one-stop TAVR+PCI in the Second Hospital of Hebei Medical University from January 2016 to May 2024 were collected,and the patients were divid-ed into CPB group and non-CPB group according to whether CPB was used during the operation,and the perioper-ative data of the two groups were retrospectively analyzed.Results:There were 40 cases in the CPB group and 12 in the non-CPB group.In the CPB group,there were 35 cases in which CPB was established but not opened,and 5 cases in which CPB was established and opened(the actual application rate of CPB was 12.5％).Fifty patients completed surgery,and 2 patients(3.8％)died intraoperatively(all in the non-CPB group).Perioperative TAVR was performed in 48 cases and transapical TAVR in 2 cases.Intraoperative PCI successfully opened single coro-nary artery stenosis in 38 cases and double coronary artery stenosis in 12 cases.The clinical symptoms of all the 50 patients were improved to different degrees after operation.There was no significant difference in the incidence of complications such as conversion to thorax opening,midvalve insertion,moderate or above perivalvular regurgi-tation,new conduction block and low cardiac production syndrome between the two groups.There was no signifi-cant difference between the two groups in postoperative ventilator assistance time,ICU monitoring time and post-operative hospitalization time.Conclusion:The application of CPB in one-stop TAVR+PCI can obtain satisfactory clinical efficacy.
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