Progress of molecular targeted therapy in acute myeloid leukemia
Acute myeloid leukemia(AML)is a highly heterogeneous hematologic malignancy.The conven-tional treatment of AML is cytotoxic chemotherapy.However,the overall survival of AML is not ideal and the 5-year survival rate is less than 30%.Recently,a series of novel molecular targeted drugs have been developed.These drugs have significantly improved the prognosis of patients with AML and provided more treatment op-tions.This article reviews the progress of molecular targeted therapy in AML.