Evans syndrome with both warm and cold antibodies after umbilical cord blood transplantation:a case report and literature review
Reports on Evans syndrome are relatively rare at home and abroad,and Evans syndrome with both warm and cold antibodies is even rarest.We reported a case of severe aplastic anemia patient who had implantation failure after the first umbilical cord blood transplantation,and the second umbilical cord blood transplantation caused Evans syndrome with both warm and cold antibodies due to virus infection.After giving rituximab com-bined with plasma exchange,all the indexes were significantly improved.The authors suggest that the combina-tion and sequential use of plasma exchange and rituximab should be considered as early as possible in patients with Evans syndrome who have not responded well to conventional therapy.