首页|非血缘脐血移植后兼有温冷双抗体Evans综合征1例并文献复习

非血缘脐血移植后兼有温冷双抗体Evans综合征1例并文献复习

扫码查看
Evans综合征国内外报道较为少见,兼有温冷双抗体Evans综合征更为罕见.文章报道了 1例重型再生障碍性贫血患者行首次非血缘脐血移植后发生植人失败,再次输入非血缘脐血植入后病毒感染下引发兼有温冷双抗体Evans综合征,给予利妥昔单抗联合血浆置换治疗后患者各项指标均明显好转.笔者建议对于移植后早期并发Evans综合征的患者在给予传统方案治疗效果差时,应尽早考虑血浆置换和利妥昔单抗的联合和序贯应用.
Evans syndrome with both warm and cold antibodies after umbilical cord blood transplantation:a case report and literature review
Reports on Evans syndrome are relatively rare at home and abroad,and Evans syndrome with both warm and cold antibodies is even rarest.We reported a case of severe aplastic anemia patient who had implantation failure after the first umbilical cord blood transplantation,and the second umbilical cord blood transplantation caused Evans syndrome with both warm and cold antibodies due to virus infection.After giving rituximab com-bined with plasma exchange,all the indexes were significantly improved.The authors suggest that the combina-tion and sequential use of plasma exchange and rituximab should be considered as early as possible in patients with Evans syndrome who have not responded well to conventional therapy.

umbilical cord blood transplantationEvans syndromesevere aplastic anemiaplasma exchangerituximab

时月、孙艳花、李乾鹏、徐曼、刘昊东、冉学红

展开 >

山东第二医科大学(临床医学院)(山东潍坊,261000)

潍坊市人民医院血液科

非血缘脐血移植 Evans综合征 重型再生障碍性贫血 血浆置换 利妥昔单抗

2024

临床血液学杂志
华中科技大学同济医学院血液病研究所 北京医科大学血液病研究所

临床血液学杂志

CSTPCD
影响因子:1.063
ISSN:1004-2806
年,卷(期):2024.37(3)
  • 20