Research on the characteristics of thromboelastography in elderly individuals
Objective:To explore the characteristics of the elderlys thrombelastogram in order to provide more comprehensive and accurate guidance for geriatric diseases.Methods:Retrospective analysis of Healthy elderly people aged 60-83 were selected from January 2021 to December 2022 at our Hospital.Thromboelastography in-struments from Leopold Company in Beijing were used for testing,and statistical analysis was conducted on pa-rameters such as clotting angle(α-angle),clot formation time(K),maximum amplitude(MA),clotting reaction time(R),clotting index(CI),predicted clot dissolution percentage(EPL),fibrinolysis index(LY30),and clot me-chanical strength(G).Results:Compared with the reference values provided by the manufacturer,the α angle and G value in elderly individuals were higher,while LY30 and EPL were significantly reduced,with statistical signifi-cance(P<0.05).Comparing the thromboelastography parameters of healthy elderly individuals with those of healthy young individuals,except for R and G,there were statistically significant differences among the other pa-rameters.Conclusion:There were differences between the reference ranges of thromboelastography in elderly indi-viduals,the ranges provided by the manufacturer,and those of healthy young individuals.Therefore,appropriate reference ranges should be established based on population characteristics to guide clinical practice.