摘要
目的:探讨老年人血栓弹力图(TEG)的特点,以便更全面准确地对老年性疾病进行指导.方法:回顾性分析2021年1月-2022年12月医院体检科健康老年人,年龄60～83岁,用北京乐普公司TEG仪进行检测,并对其凝血形成速率(α角)、血凝块溶解百分比(EPL)、凝血反应时间(R)、凝血形成时间(K)、凝血最大强度(MA)、凝血综合指数(CI)、纤维蛋白溶解指数(LY30)和血凝块力学强度(G)等数据进行统计分析.结果:与厂家提供的TEG参考值比较,老年人的α角、G值偏大,LY30、EPL明显减小,差异有统计学意义(P＜0.05);将健康老年人的TEG参数与健康年轻人比较,除R和G以外,其余各参数之间差异有统计学意义(P＜0.05).结论:老年人的TEG参考区间与厂商提供及健康年轻人的参考区间存在差异,应根据人群特点制定相应的参考范围指导临床.
Abstract
Objective:To explore the characteristics of the elderlys thrombelastogram in order to provide more comprehensive and accurate guidance for geriatric diseases.Methods:Retrospective analysis of Healthy elderly people aged 60-83 were selected from January 2021 to December 2022 at our Hospital.Thromboelastography in-struments from Leopold Company in Beijing were used for testing,and statistical analysis was conducted on pa-rameters such as clotting angle(α-angle),clot formation time(K),maximum amplitude(MA),clotting reaction time(R),clotting index(CI),predicted clot dissolution percentage(EPL),fibrinolysis index(LY30),and clot me-chanical strength(G).Results:Compared with the reference values provided by the manufacturer,the α angle and G value in elderly individuals were higher,while LY30 and EPL were significantly reduced,with statistical signifi-cance(P＜0.05).Comparing the thromboelastography parameters of healthy elderly individuals with those of healthy young individuals,except for R and G,there were statistically significant differences among the other pa-rameters.Conclusion:There were differences between the reference ranges of thromboelastography in elderly indi-viduals,the ranges provided by the manufacturer,and those of healthy young individuals.Therefore,appropriate reference ranges should be established based on population characteristics to guide clinical practice.
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