Interpretation of expert consensus on diagnosis and treatment of disseminated intravascular coagulation in obstetrics
Disseminated intravascular coagulation(DIC)is an acquired syndrome characterized by the intravas-cular activation of coagulation with a loss of localization arising from different causes.It can originate from and cause damage to the microvasculature,which if sufficiently severe,can produce organ dysfunction.On the basis of physiologic hypercoagulability in pregnant women,it is easy to induce DIC if placental abruption,preeclampsia,HELLP syndrome,amniotic fluid embolism,infection and other serious conditions are complicated.The clinical manifestations show the characteristics of rapid onset and rapid change,and are prone to severe shock and multiple organ failure,which seriously affect the survival and health of mothers and infants.To improve the awareness of Chinese clinical workers about this disease,reduce maternal and fetal mortality,and improve pregnancy out-comes,the Hematology branch of the Chinese Medical Association formulated the"Chinese Expert Consensus on Clinical Diagnosis and Treatment of Obstetric Disseminated Intravascular Coagulation".This article interprets the pathogenesis,clinical manifestations,laboratory tests,diagnostic criteria and treatment of obstetric DIC in the consensus.
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