Utilization of platelet-rich plasma together with vacuum sealing drainage for managing intractable diabetic ulcers
Objective:To discuss the difference of clinical efficacy of vacuum sealing drainage(VSD)and au-tologous platelet-rich plasma(PRP)combined with VSD in the treatment of intractable wounds in diabetic patients by means of comparative analysis.Methods:A group of sixty-four patients with diabetes suffering from persistent wounds,who were admitted to the endocrine department of the hospital from June 2022 to December 2023,were divided into a pair of cohorts,each consisting of 32 individuals.The first cohort underwent conventional VSD ther-apy,and the second was subjected to a combined treatment of VSD and PRP,according to the distinct treatment plans set for each group.VSD technology was applied to the control group,and PRP combined with VSD technol-ogy was applied to the observation group.We assessed the efficacy of treatment by comparing and monitoring the pace of recovery as well as the duration of wound closure between two cohorts.Results:Findings indicated that the rate at which wounds closed in the treatment cohort surpassed that of the comparison cohort(P＜0.05),and the period required for complete healing in the treatment cohort was notably reduced compared to the comparison co-hort(P＜0.05).Conclusion:When PRP was used in conjunction with VSD,it could significantly enhance the rate of wound recovery,reduce the duration of healing,and exhibit a superior therapeutic outcome.
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