首页|云南怒江州地区居民高尿酸血症现状及相关因素分析

云南怒江州地区居民高尿酸血症现状及相关因素分析

扫码查看
目的:了解云南怒江州地区人群高尿酸血症(hyperuricemia,HUA)的患病率,并探讨与之相关的危险因素.方法:选取怒江傈僳族自治州人民医院2020年8月—2023年7月17 183例体检者的临床资料作为研究对象,收集其尿酸(uric acid,UA)、甘油三酯、总胆固醇、低密度脂蛋白、空腹血糖等生化检测指标,回顾性分析不同年龄、不同性别人群HUA患病率的变化,探讨UA水平与血糖、血脂等临床指标的相关性.结果:云南怒江州地区体检人群中,HUA患病率为48.45%,患者以40岁以下的中青年男性为主.在男性人群中,无论UA高低,胆固醇检测值无明显差异,而在女性人群中差异有统计学意义(P<0.05);不同UA水平的人群,男性和女性的低密度脂蛋白检测值差异有统计学意义(P<0.05);不同UA水平的人群,男性和女性的甘油三酯检测值差异有统计学意义(P<0.05);在男性人群中,不同UA水平空腹血糖检测值差异有统计学意义(P<0.05),而女性人群中差异无统计学意义.从总体趋势来看,HUA与甘油三酯、总胆固醇、低密度脂蛋白异常升高呈正相关;与空腹血糖升高呈负相关.结论:云南怒江州地区人群HUA发生率较高,应重点关注该地区中青年男性居民,加强UA、血脂水平的控制.
Analysis of current situation and related factors of hyperuricemia among residents in Nujiang prefecture of Yunnan
Objective:To investigate the prevalence of hyperuricemia(HUA)in the population of Nujiang Pre-fecture,Yunnan,and explore the associated risk factors.Methods:Clinical data of 17 183 physical examiners from the Nujiang Lisu Autonomous Prefecture Peoples Hospital from August 2020 to July 2023 were selected as the research subjects.Biochemical indicators such as uric acid,triglycerides,total cholesterol,low-density lipo-protein,and fasting blood glucose were collected.The changes in the prevalence of HUA in different age and gen-der groups were retrospectively analyzed,and the correlation between uric acid levels and clinical indicators such as blood glucose and blood lipids was explored.Results:The prevalence of HUA among the physical examination population in Nujiang Prefecture,Yunnan was 48.45%,with the majority of patients being middle-aged and young men under the age of 40.In the male population,there was no significant difference in cholesterol detection values regardless of the level of uric acid,while there was a statistical difference in the female population(P<0.05);there were statistically significant differences in low-density lipoprotein detection values between males and females with different levels of uric acid(P<0.05);there was a statistically significant difference in triglyceride detection values between males and females with different levels of uric acid(P<0.05);in the male population,there was a statistically significant difference in fasting blood glucose detection values at different levels of uric acid(P<0.05),while there was no statistically significant difference in the female population.From the overall trend,high uric acid was positively correlated with abnormal increases in triglycerides,total cholesterol,and low-density lipoprotein;while it was negatively correlated with elevated fasting blood sugar.Conclusion:The incidence of HUA in the population of Nujiang Prefecture,Yunnan was relatively high,and special attention should be paid to young and middle-aged male residents in the area to strengthen the control of uric acid and blood lipid levels.

hyperuricemiablood sugarblood lipidsrelated factorsNujiang prefecture

赵晓明、王彦涛、张霜燕、贾勤

展开 >

同济大学附属东方医院南院检验科(上海,200120)

怒江傈僳族自治州人民医院检验科

高尿酸血症 血糖 血脂 相关因素 怒江

2024

临床血液学杂志
华中科技大学同济医学院血液病研究所 北京医科大学血液病研究所

临床血液学杂志

CSTPCD
影响因子:1.063
ISSN:1004-2806
年,卷(期):2024.37(12)