Study on choroidal and retinal thickness in school-age children with hyperopic amblyopia
Objective To study the distribution and changes of choroidal thickness and retinal thickness in chil-dren with different degrees of amblyopia.Methods A prospective case-control study.A total of 48 children(96 eyes)with hyperopic amblyopia were divided into the mild(34 eyes),moderate(34 eyes)and severe(28 eyes)groups according to the severity of amblyopia,and 17 children(34 eyes)with normal vision in the same period were selected as the emmetropia group.Enhanced depth imaging optical coherence tomography(EDI-OCT)subfoveal choroidal thickness(SFCT),1.0mm from fovea,nasal(N1,N3)and temporal(T1,T3)choroidal thickness(CT)and macular foveal retinal thickness(FRT)were measured.Age,sex,visual acuity,axis length(AL)and spherical equivalent(SE)were recorded.The correlations between CT and RT,AL,SE and age,as well as between RT and AL and age were analyzed.Results The CT of five positions in each group thickened with the aggravation of amblyopia,and there were significant differences among the three groups(P<0.05).The CT of the moderate hyperopic amblyopia group was thicker than that of the emmetropia group,and only SFCT and N3 CT of the moderate hyperopic amblyopia group were thicker than those of the mild amblyopia group.The CT of the severe hyperopic amblyopia group was significantly thicker than that of the other three groups(P<0.05).In hyperopic am-blyopia group,SFCT was thicker than the other four positions,and T1 and T3 were thicker than N1 and N3,respectively,and N1 was thicker than T3 and N3,respectively(P<0.05).FRT in the four groups tended to thicken with the aggravation of amblyopia,but there was no significant difference among the four groups(P>0.05).In the hyperopic amblyopia group,SFCT was negatively correlated with AL,positively correlated with FRT and SE(P<0.05),FRT was negatively correlated with AL(P<0.05),and SFCT,FRT had no correlation with age(P>0.05).Conclusions Amblyopia in children with hy-peropic amblyopia can affect the choroidal tissue structure of the macular area.
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