Analysis of factors related to short-term visual prognosis in patients with high myopia secondary to macular neovascularization after anti VEGF surgery
Objective Explore the relevant factors that affect the short-term visual prognosis of patients with high myopic macular neovascularization(MNV)treated with anti vascular endothelial growth factor(VEGF).Methods Retro-spective analysis of the clinical data of 28 cases(28 eyes)of high myopia with secondary MNV who received anti VEGF treatment at the Ophthalmology Department of the First Affiliated Hospital of Anhui University of Technology from January 2021 to June 2023.Divide the best corrected visual acuity(BCVA)one month after surgery into a poor visual prognosis group and a good visual prognosis group.Compare the preoperative eye characteristics and related biological parameters of the two groups of patients and conduct statistical analysis.Results After one month of anti VEGF treatment,the BCVA,central macular thickness(CMT),and MNV area of patients with high myopia secondary to MNV significantly improved compared to before surgery,with statistical differences(Z=6.371,6.949,2.437,P<0.05).Univariate analysis showed that there was a statistically significant difference in axial length,posterior staphyloma,CMT improvement,and MNV area im-provement between the two groups of patients(both P<0.05).Multivariate Logistic regression analysis showed that axial length and preoperative MNV area were independent influencing factors for visual prognosis in MNV patients after anti VEGF treatment(P<0.05).Conclusions Anti VEGF therapy for high myopia secondary to MNV can effectively improve patients'vision.Postoperative vision is related to axial length,posterior staphyloma,improvement in CMT,and improve-ment in MNV area.Among them,axial length and preoperative MNV area are independent influencing factors on visual prognosis
High myopiamacular neovascularizationanti VEGFvisual prognosis
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