首页|IPL治疗MGD相关性干眼的临床疗效及其对患者眼表功能的影响

IPL治疗MGD相关性干眼的临床疗效及其对患者眼表功能的影响

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目的 睑板腺功能障碍(MGD)相关性干眼患者接受强脉冲光(IPL)治疗对干眼症状、心理状态等的影响.方法 前瞻性病例对照研究.60例研究对象均选自我院2019年10月至2022年10月收治的MGD相关性干眼患者,随机数字表法将其分为对照组和观察组,各30例.对照组患者接受常规治疗结合睑板腺按摩,观察组则在对照组基础上进行IPL治疗,治疗时间8周.比较两组患者治疗后临床疗效、治疗前后心理状态、干眼相关指标以及治疗期间并发症发生情况.结果 治疗后,观察组患者的临床总有效率与对照组相比较高;与治疗前比,治疗后两组焦虑自评量表(SAS)、抑郁自评量表(SDS)、眼表疾病指数量表(OSDI)、角膜荧光素钠染色评分(CFS)得分均降低,且观察组低于对照组;泪液分泌实验结果(SIt)长度增长,且观察组长于对照组;泪膜破裂时间(BUT)时间延长,且观察组长于对照组;治疗期间,对照组并发症总发生率高于观察组,差异有统计学意义(P<0.05).结论 MGD相关性干眼以IPL联合睑板腺按摩进行治疗能够有效缓解干眼症状,减轻焦虑抑郁等负面情绪,降低并发症发生风险,对治疗效果进行了进一步优化.
Clinical efficacy of IPL in the treatment of MGD-associated dry eye and its effect on ocular function
Objective To investigate the effects of intense pulsed light(IPL)on dry eye symptoms and mental state in patients with meibomian gland dysfunction(MGD)associated with dry eye.Methods A prospective case-control study.Sixty patients with MGD-related dry eye who were admitted to our hospital from October 2019 to October 2022 were selected,and randomly divided into the control group and the observation group,with 30 cases in each group.The control group received conventional treatment combined with meibomian gland massage,and the observation group received IPL treatment on the basis of the control group,and the treatment duration was 8 weeks.The clinical efficacy,mental state,dry eye related indicators and after the treatment and complications during the treatment were compared between the two groups.Results After the treatment,the total effective rate of the observation group was higher than that of the control group.Compared with before the treatment,the scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS),ocular surface disease index(OSDI)and corneal fluorescein sodium staining score(CFS)in the two groups decreased after treatment,and the observation group was lower than the control group.The length of SIt increased,and the observation group was longer than the control group.The break-up time(BUT)prolonged,and the observation group was longer than the control group.During treatment,the total complication rate of the control group was higher than that of the observation group,the difference was statistically significant(P<0.05).Conclusions The treatment of MGD-related dry eye with IPL combined with meibomian gland massage can effectively relieve the symptoms of dry eye,reduce anxiety,depression and other negative emotions,reduce the risk of complications,and further optimize the therapeutic effect.

Meibomian gland dysfunctionDry eyeIntense pulsed lightMental state

产竹林、江彤彤

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246000 安庆,海军安庆医院眼科

睑板腺功能障碍 干眼 强脉冲光 心理状态

2024

临床眼科杂志
安徽医科大学,安徽眼科研究所

临床眼科杂志

CSTPCD
影响因子:0.791
ISSN:1006-8422
年,卷(期):2024.32(2)
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