Observation of the effectiveness and safety of intravenously assisted sedative analgesic anesthesia combined with retrobulbar anesthesia in vitrectomy surgery
Objective To observe the effectiveness and safety of pure peribulbar anesthesia versus combined in-travenous sedation and analgesia with peribulbar anesthesia in vitrectomy surgery.Methods A prospective clinical study.This study included 200 patients who underwent elective vitrectomy surgery at our hospital between February 2022 and June 2023.The patients were randomly assigned into two groups:the control group(n=100)received peribulbar block an-esthesia alone,while the combination group(n=100)received intravenous sedation and analgesia combined with peribul-bar block anesthesia.Mean arterial pressure(MAP),heart rate(HR),oxygen saturation(SpO2),and sedation scores were recorded at various time points:10 minutes of rest after admission(T0),during peribulbar block injection(T1),30 minutes into the surgery(T2),and at the end of surgery(T3).Pain incidence at T1 and adverse reactions during the surgery were also noted.Additionally,state anxiety inventory(S-AI)scores were recorded 30 minutes before surgery and at the end of surgery,along with satisfaction scores from the primary surgeon and patients.Results At T1,T2,and T3,the com-bination group had significantly lower MAP and HR scores compared to the control group,while Ramsay sedation scores were significantly higher(all P<0.05).No statistically significant difference in SpO2 was observed between the groups at any time point.At T1,the pain incidence in the combination group was 39%lower than in the control group.No cases of nausea,vomiting,or respiratory depression occurred in either group during surgery.Preoperative S-AI scores 30 minutes before the surgery did not significantly differ between the groups(P=0.095).However,postoperative S-AI scores were sig-nificantly lower in the combination group(P<0.001).Both surgeon and patient satisfaction scores were significantly higher in the combination group(P<0.001).Conclusions Utilizing intravenous sedation and analgesia combined with peribulbar block anesthesia during vitrectomy surgery helps maintain hemodynamic stability,enhances patient satisfaction and comfort,and improves overall procedural safety.
Simple retrobulbar anesthesiaIntravenous assisted sedation and analgesic anesthesia combined with retrobulbar anesthesiaVitrectomy surgery
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