Differences in retinal structural parameters in patients with high myopia and glaucoma
Objective To investigate the differences in retinal structural parameters in patients with high myopia(HM)and high myopia combined with open-angle glaucoma(HMG).Methods The clinical study subjects included 20 patients with 36 eyes and 21 patients with HMG patients with 35 eyes.The demographic and clinical characteristics of the two groups of patients such as age,visual acuity,intraocular pressure,and visual field were recorded,and the thickness of the retinal nerve fiber layer(RNFL)and the macular thickness were scanned by optical coherence tomography(OCT),and optical coherence tomography was used to scan the angiographic imaging technology angiography,(OCTA)scans the vessel density(VD)at the three levels of macula,superficial capillary plexus centered on the optic disc,deep capillary plexus and choroidal capillary plexus,and then calculates the VD vessel density ratio(VDR)in the upper and lower halves respectively,and finally performs statistical analysis.Results The HM group was higher than the HMG group in the upper,lower,temporal and central thickness parameters of RNFL,which had significant statistical significance(all P<0.001).The macular thickness of all 9 partitions in the HM group was greater than that in the HMG group,but the only areas with statistical differences were the inferior inner layer,temporal side and inferior outer layer(all P<0.05).The VD in both the macula and optic disc was lower than that in the HMG group(all P<0.05),and the reduction of blood flow density in the lower area of SCP was the most obvious,and only the VDR of SCP was statistically different(all P<0.05).Conclusions Structural parameters such as peripapillary RNFL thickness,macular thickness,optic disc and macular blood flow density are helpful for the clinical diagnosis of HMG,and the reduction of SCP VDR may further improve the di-agnostic efficacy.
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