Effect of hydroxypropy l methylcellulose on the ocular surface during cataract phacoemulsification
Objective To explore the effect of hydroxypropyl methylcellulose(HPMC)on the ocular surface dur-ing cataract phacoemulsification.Methods A prospective case-control study.30 elderly cataract patients admitted to our hospital from January 2022 to December 2023 were randomly divided into an experimental group(HPMC group)and a con-trol group.The control group cornea was washed with balanced salt solution(BSS)during the surgery,while the experi-mental group was treated with 2%HPMC during the surgery.The ocular surface disease index(OSDI),breaking up time(BUT),and corneal fluorescence staining were evaluated beforeand at 1 day,1 week,and 4 weeks after the surgery,and a statistical analysis on was performed on the results.Results The OSDI score of the HPMC group was lower than that of the control group at 1 day,1 week,and 4 weeks after the surgery,and the difference was statistically significant.The BUT in the HPMC group was higher than that in the control group at 1 day,1 week,and 4 weeks after the surgery,and the dif-ference was statistically significant.1 day and 1 week after the surgery,the corneal fluorescein staining score of the HPMC group was lower than the control group with statistical differences.At 4 weeks after the surgery,there was no significant dif-ference in corneal fluorescein staining score between the two groups.Conclusions The use of HPMC on the cornea during cataract phacoemulsification surgery can improve the postoperative ocular surface condition of patients and enhance the protective effect on the cornea.
万方数据
维普
