Comparison of the effects on cataract surgery with and without the utilization of optional parameters in the new generation intraocular lens calculation formulas
Objective To evaluate the contribution of lens thickness(LT)and central corneal thickness(CCT)measurements to the prediction error of target refraction after cataract surgery using the Emmetropia Verifying Optical(EVO)and Kane formula.Methods A retrospective case-control study.Measurements taken with the intraocular lens(IOL)Master 700 swept-source biometry of 203 right eyes of 203 consecutive patients undergoing cataract extraction sur-gery in the First Affiliated Hospital of Soochow University from July to December 2021 were collected and analyzed.The IOL power was calculated using EVO and Kane formula,first through the inclusion of all measured variables and then by using partial biometry data.The patients were divided into groups according to the axial length(AL),and the differences in calculation results under different conditions and the influence on the prediction error of postoperative target refraction were compared.Results EVO and Kane formulas showed similar prediction error distribution range to BUII formula.No matter EVO or Kane formula,the difference in MAE value of target refraction calculated under the condition of omitting LT,omitting LT and CCT at the same time were significant compared with all variables(P<0.01).The optional variable CCT had little value in the above two formulas(the mean absolute of all variables when omitting CCT compared with all variables:EVO formula was 0.01 D;Kane was 0.03 D).When omitting LT and omitting LT,CCT,the optional variables have the least impact in long AL eyes(AL≥26 mm)(mean absolute difference:EVO formula was 0.07 D;Kane formula was 0.05 D),while they have the greatest impact in short AL eyes(AL≤22 mm)(mean absolute difference:EVO for-mula was 0.24 D;Kane formula was also 0.24 D).When omitting LT and omitting LT,CCT,the percentage of eyes with MAE≥0.50 D in AL≤22 mm group was the highest(66.7%).Conclusions the optional variable CCT has little value on the prognosis of cataract surgery after the calculation of IOL power using EVO and Kane formula.When the EVO and Kane formulas are calculated with partial optional variables or without optional variables,for the eyes with short AL(AL≤22 mm),there is a clinically significant difference in the prediction error of target refraction compared with all optional vari-ables after cataract surgery.In contrast,for eyes with AL more than 22 mm,the effect of optional variables on the predic-tion error of postoperative target refraction is not so important.
Intraocular lens calculationEVO formulaKane formulaCataract surgery