Effect of budesonide + azithromycin + terbutaline aerosol inhalation in the treatment of children with mycoplasma pneumonia and its influences on inflammatory response,lung function and T lymphocyte subsets
Objective To observe the effect of budesonide + azithromycin + terbutaline aerosol inhalation in the treatment of children with mycoplasma pneumonia and its influences on inflammatory response,lung function and T lymphocyte subsets.Methods A total of 84 children with mycoplasma pneumonia admitted from January to December 2021 were selected as the research objects,and randomly divided into control group and observation group,with 42 cases in each group.The control group was treated with azithromycin + terbutaline,and the observation group was treated with budesonide on the basis of the control group.The therapeutic effects of the two groups were compared.Results The disappearance time of cough,elevated body temperature,lung rales,lung lesions and negative conversion time of mycoplasma-IgM antibody in the observation group were shorter than those in the control group(P<0.05).After treatment,the levels of procalcitonin(PCT),granulocyte colony-stimulating factor(G-CSF),interleukin-6(IL-6)and ferritin in the observation group were lower than those in the control group(P<0.05).After treatment,the forced vital capacity(FVC),forced expiratory volume in one second(FEV1),maximal expiratory flow at 50%of the vital capacity(MEF50)and peak expiratory flow(PEF)in the observation group were higher than those in the control group(P<0.05).After treatment,the CD3+,CD4+ and CD4+/CD8+ in the observation group were higher than those in the control group(P<0.05).Conclusion Budesonide + azithromycin + terbutaline aerosol inhalation has a significant effect in the treatment of children with mycoplasma pneumonia,which can significantly improve the symptoms and signs of children,reduce the levels of inflammatory factors,and improve lung function and immune function.
mycoplasma pneumoniabudesonideazithromycinterbutalinelung function
NETL
NSTL
万方数据
维普
