首页|全胃切除调节型双通道间置空肠消化道重建术对进展期胃癌患者胃肠屏障功能及营养状态的影响

全胃切除调节型双通道间置空肠消化道重建术对进展期胃癌患者胃肠屏障功能及营养状态的影响

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  • NETL
  • NSTL
  • 万方数据
  • 维普
目的 探讨全胃切除调节型双通道间置空肠消化道重建术对进展期胃癌患者胃肠屏障功能及营养状态的影响。方法 选取 2019 年 1月至2022 年 1 月我院收治的 40 例进展期胃癌患者为研究对象，根据术式不同将其分为对照组和观察组，各 20例。对照组采用全胃切除Roux-en-Y吻合消化道重建术治疗，观察组采用全胃切除调节型双通道间置空肠消化道重建术治疗。比较两组的治疗效果。结果 术后，观察组的D-乳酸、二胺氧化酶(DAO)、内毒素(ETX)水平低于对照组(P＜0。05)。术后，观察组的胆囊收缩素水平、胆囊排空率、胆囊容积优于对照组(P＜0。05)。术后，观察组的白蛋白(ALB)、前白蛋白(PA)、血清铁蛋白(SF)水平高于对照组(P＜0。05)。观察组的术后并发症总发生率低于对照组(P＜0。05)。结论 全胃切除调节型双通道间置空肠消化道重建术可改善进展期胃癌患者的胃肠屏障功能、胆囊收缩功能及营养状态，降低术后并发症发生率，值得推广。
Effects of total gastrectomy and adjustable double-channel interposition jejunal digestive tract reconstruction on gastrointestinal barrier function and nutritional status in patients with advanced gastric cancer
Objective To investigate the effects of total gastrectomy and adjustable double-channel interposition jejunal digestive tract reconstruction on gastrointestinal barrier function and nutritional status in patients with advanced gastric cancer.Methods A total of 40 patients with advanced gastric cancer admitted in our hospital from January 2019 to January 2022 were selected as the research objects.According to different surgical methods,the patients were divided into control group and observation group,with 20 cases in each group.The control group was treated with total gastrectomy and Roux-en-Y anastomosis digestive tract reconstruction,and the observation group was treated with total gastrectomy and adjustable double-channel interposition jejunal digestive tract reconstruction.The therapeutic effects of the two groups were compared.Results After operation,the levels of D-lactic acid,diamine oxidase(DAO)and endotoxin(ETX)in the observation group were lower than those in the control group(P<0.05).After operation,the cholecystokinin level,gallbladder emptying rate and gallbladder volume in the observation group were better than those in the control group(P<0.05).After operation,the levels of albumin(ALB),prealbumin(PA)and serum ferritin(SF)in the observation group were higher than those in the control group(P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).Conclusion Total gastrectomy and adjustable double-channel interposition jejunal digestive tract reconstruction can improve the gastrointestinal barrier function,gallbladder contraction function and nutritional status of patients with advanced gastric cancer,and reduce the incidence of postoperative complications,which is worthy of promotion.

total gastrectomyadjustable double-channel interposition jejunal digestive tract reconstructionadvanced gastric cancer

高永江、刘杰、田利军、吴智斌、化建彪

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神木市医院,陕西 榆林,719300

全胃切除术 调节型双通道间置空肠消化道重建术 进展期胃癌

2024

10.19347/j.cnki.2096-1413.202401022

临床医学研究与实践

临床医学研究与实践

ISSN：
年,卷(期)：2024.9(1)
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