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健脾和肠汤联合西药治疗儿童急性肠炎的效果

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目的 探究健脾和肠汤联合西药治疗儿童急性肠炎的效果。方法 选择 2020 年 6 月至 2022 年 4月在儿科住院的80例急性肠炎患儿为研究对象,按用药方式不同将其分为联合组和西药组,各40 例。西药组采用常规西药治疗,联合组在西药组基础上联合应用健脾和肠汤治疗。比较两组的治疗效果。结果 联合组的治愈率高于西药组,差异具有统计学意义(P<0。05);两组的治疗总有效率比较,差异无统计学意义(P>0。05)。联合组的退热时间、大便次数正常时间、大便质地正常时间及住院时间短于西药组,差异具有统计学意义(P<0。05)。治疗后,联合组的腹痛、大便次数、大便性质、腹胀、神疲懒言、肢体困倦评分低于西药组,差异具有统计学意义(P<0。05)。治疗后,联合组的C反应蛋白(CRP)、白细胞介素-6(IL-6)水平及CD8+低于西药组,CD4+高于西药组,差异具有统计学意义(P<0。05)。两组患儿治疗过程中均未出现明显不良反应。结论 健脾和肠汤联合西药治疗能有效缓解急性肠炎患儿的各项症状,提升治愈率,调节炎性因子及免疫功能指标水平,安全性较高,值得在临床中推广及应用。
Effect of Jianpi Hechang decoction combined with western medicine in the treatment of acute enteritis in children
Objective To explore the effect of Jianpi Hechang decoction combined with western medicine in the treatment of acute enteritis in children.Methods A total of 80 children with acute enteritis who were hospitalized in pediatrics department from June 2020 to April 2022 were selected as the research objects.The children were divided into combined group and western medicine group according to different medication methods,with 40 cases in each group.The western medicine group was treated with conventional western medicine,and the combined group was treated with Jianpi Hechang decoction on the basis of the western medicine group.The therapeutic effects of the two groups were compared.Results The cure rate of the combined group was higher than that of the western medicine group,and the difference was statistically significant(P<0.05);there was no significant difference in the total effective rate of treatment between the two groups(P>0.05).The antipyretic time,normal stool frequency time,normal stool texture time and hospitalization time of the combined group were shorter than those of the western medicine group,and the differences were statistically significant(P<0.05).After treatment,the scores of abdominal pain,stool frequency,stool property,abdominal distension,lassitude and limb sleepiness in the combined group were lower than those in the western medicine group,and the differences were statistically significant(P<0.05).After treatment,the C-reactive protein(CRP),interleukin-6(IL-6)levels and CD8+ in the combined group were lower than those in the western medicine group,and the CD4+ was higher than that in the western medicine group,the differences were statistically significant(P<0.05).There was no obvious adverse reactions in the two groups during the treatment.Conclusion Jianpi Hechang decoction combined with western medicine can effectively alleviate the symptoms of children with acute enteritis,improve the cure rate,regulate the levels of inflammatory factors and immune function indexes,and has high safety,which is worthy of promotion and application in clinical practice.

acute enteritischildJianpi Hechang decoctionwestern medicine

毋荣荣、刘智刚、马小兵

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宝鸡市第二中医医院,陕西 宝鸡,721001

陕西中医药大学第二附属医院,陕西 咸阳,712000

急性肠炎 儿童 健脾和肠汤 西药

2021年度陕西中医药大学校级科研课题立项

2021GP44

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(1)
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