Effect of blood lipid index on the incidence of sudden sensorineural hearing loss
Objective To explore the effect of blood lipid index on the incidence of sudden sensorineural hearing loss(SSNHL),and to provide reference for the selection of auxiliary diagnostic indicators for SSNHL.Methods A total of 198 patients with SSNHL who were hospitalized in the otolaryngology department of Nantong Tongzhou People's Hospital from January 2017 to December 2022 were selected as the SSNHL group.In addition,198 patients who were hospitalized in our hospital during the same period,whose general data were matched with the SSNHL group and had no ear disease were selected as the control group.The gender,age,body mass index,types of chronic diseases and blood lipid of the two groups were collected and compared,and the influencing factors for the incidence of SSNHL were analyzed.Results The results of univariate analysis showed that there were no significant differences in gender,age,body mass index,proportion of diabetes mellitus,hypertension,coronary heart disease,triglyceride(TG),high density lipoprotein-cholesterol(HDL-C),apolipoprotein AⅠ(apo AⅠ)and apolipoprotein B(apo B)levels between the two groups(P>0.05);there were statistically significant differences in the levels of total cholesterol(TC),low density lipoprotein-cholesterol(LDL-C)and lipoprotein(a)[LP(a)]between the two groups(P<0.05).Multivariate Logistic regression analysis showed that TC and LDL-C were independent influencing factors for the incidence of SSNHL(P<0.05).Conclusion TC and LDL-C are independent influencing factors for the incidence of SSNHL,which may play an important role in the pathogenesis of SSNHL.Therefore,the clinical diagnosis of SSNHL should focus on the levels of TC and LDL-C as routine indicators for auxiliary diagnosis.
sudden sensorineural hearing losstotal cholesterollow density lipoprotein-cholesterolblood lipid index