Research progress of inflammatory markers and post-stroke depression
Post-stroke depression(PSD)is a bio-psycho-social disease that affects individuals who have stroke at any point in time.The prevalence of PSD in survivors of ischemic stroke(IS)is 20%-60%.The prognosis of PSD is poor,and if not intervened or treated early,severe cases can lead to disability.Immune and inflammatory responses play important roles in the occurrence and development of IS,and the elevation of inflammatory markers caused by IS may play an important role in the pathogenesis of depressive symptoms.In recent years,many scholars at home and abroad have studied the relationship between neuroinflammation and PSD.This article reviews the research progress of neuroinflammation in PSD,aiming to provide a more comprehensive reference for the comprehensive diagnosis and treatment of PSD.
post-stroke depressionischemic strokeneutrophilslymphocytesystemic immune-inflammation index
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