Comparison of the application effect of esketamine and remifentanil combined with propofol in outpatient painless hysteroscopy examination
Objective To compare the application effect of esketamine and remifentanil combined with propofol in outpatients painless hysteroscopy examination.Methods A total of 60 patients who voluntarily received painless hysteroscopy examination in Shaanxi Provincial People's Hospital from October to November 2021 were selected as the research objects.According to the random number table method,the patients were divided into group A and group B,with 30 cases in each group.The group A were slowly injected with 0.5 mg/kg of esketamine and 1.5 mg/kg of propofol,while the group B were slowly injected with 0.5 μg/kg of remifentanil and 1.5 mg/kg of propofol.The incidences of perioperative respiratory depression,hypotension,nausea and vomiting and body movement in the two groups were recorded;the recovery time,dosage of propofol and Numerical Rating Scale(NRS)score at 10 and 30 min after operation were recorded in the two groups;the patient satisfaction and surgeon satisfaction scores were compared between the two groups.Results The incidences of respiratory depression and hypotension in the group A were significantly lower than those in the group B,and the differences were statistically significant(P<0.05);there were no significant differences in the incidences of nausea and vomiting and body movement between the two groups(P>0.05).There was no significant difference in the recovery time between the two groups(P>0.05);the amount of propofol used in the group A was significantly less than that in the group B,and the NRS score at 10 and 30 min after operation were significantly lower than those in the group B,and the differences were statistically significant(P<0.05).There were no significant differences in the satisfaction scores of patients and surgeons between the two groups(P>0.05).Conclusion Compared with remifentanil combined with propofol,the esketamine combined with propofol in outpatient painless hysteroscopy examination has satisfactory anesthetic effect,with less adverse reactions during operation and less postoperative pain,which is worthy of clinical promotion and application.