Effect of CT-guided radiofrequency ablation on patients with hepatocellular carcinoma and its influences on AST and ALT levels
Objective To investigate the effect of CT-guided radiofrequency ablation on patients with hepatocellular carcinoma and its influences on aspartate aminotransferase(AST)and alanine aminotransferase(ALT)levels.Methods A total of 40 patients with hepatocellular carcinoma admitted in our hospital from August 2019 to August 2022 were selected as the research objects.According to the random number table method,the patients were divided into control group(20 cases,transcatheter arterial chemoembolization)and observation group(20 cases,CT-guided radiofrequency ablation + transcatheter arterial chemoembolization).The therapeutic effects of the two groups were compared.Results After treatment,the levels of AST,ALT,total bilirubin(TBIL)and α-fetoprotein(AFP)in the observation group were lower than those in the control group(P<0.05).After treatment,CD3+,CD4+ and CD4+/CD8+ in the observation group were higher than those in the control group,and CD8+ was lower than that in the control group(P<0.05).The total effective rate of recent treatment and the total incidence of complications in the observation group were better than those in the control group(P<0.05).Conclusion CT-guided radiofrequency ablation can significantly improve the liver function and immune function of patients with hepatocellular carcinoma,regulate AFP level,and has low incidence of complications and higher safety.