Comparison of application value of self-crosslinked sodium hyaluronate gel and absorbent cotton filling in endoscopic dacryocystorhinostomy for chronic dacryocystitis
Objective To compare the clinical value of self-crosslinked sodium hyaluronate gel and absorbent cotton filling in endoscopic dacryocystorhinostomy for chronic dacryocystitis.Methods Forty-eight patients with chronic dacryocystitis who underwent endoscopic dacryocystorhinostomy from February 2020 to March 2022 were selected as the study objects,and the patients were divided into control group and observation group according to random number table method,with 24 cases in each group.The patients in both groups were given endoscopic dacryocystorhinostomy,the control group was filled with absorbent cotton,and the observation group was filled with self-crosslinked sodium hyaluronate gel.The therapeutic effects of the two groups were compared.Results After operation,the comfort score of the observation group was lower than that of the control group,and the degree of bleeding was better than that of the control group(P<0.05).After operation,the levels of norepinephrine(NE),cortisol(Cor),epinephrine(E),tumor necrosis factor-α(TNF-α),procalcitonin(PCT)and matrix metalloproteinase-3(MMP-3)in the observation group were lower than those in the control group(P<0.05).After operation,the score of tear overflow degree in the observation group was lower than that in the control group,and break-up time(BUT)was longer than that in the control group(P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).Conclusion In patients with chronic dacryocystitis undergoing endoscopic dacryocystorhinostomy,the self-crosslinked sodium hyaluronate gel filling has more obvious curative effect,with less postoperative blood seepage and less trauma,it can alleviate pain and improve comfort level,reduce stress response and inflammatory factor secretion,and reduce the incidence of postoperative complications,which is worth promoting.
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NSTL
万方数据
维普
