摘要
非典型帕金森综合征(APS)是一组类似于帕金森病(PD)的神经退行性疾病,包括多系统萎缩(MSA)、路易体痴呆(DLB)、进行性核上性麻痹(SP)、皮质基底节变性(CBD)等.随着人口老龄化进程的加剧,APS等神经退行性疾病的发病率不断上升.目前,APS的诊断取决于"危险信号"被识别的可能性,包括早期频繁跌倒、早期认知障碍、进展更快、对左旋多巴反应差等.近年来,随着研究的进展,发现APS患者的眼球运动有着不同程度的障碍,且眼动评估具有非侵入性的优势,对于APS有一定的辅助诊断价值.故本文将对APS的眼球运动障碍方面进行系统性综述.
Abstract
Atypical Parkinson's syndrome(APS)is a group of neurodegenerative diseases similar to Parkinson's disease(PD),including multiple system atrophy(MSA),dementia with lewy body(DLB),progressive supranuclear palsy(PSP),corticobasal degeneration(CBD),etc.With the aging process of the population,the incidence of neurodegenerative diseases such as APS is increasing.At present,the diagnosis of APS depends on the possibility of"danger signals"being recognized,including early frequent falls,early cognitive impairment,faster progression,poor response to levodopa,etc.In recent years,with the research progress,it has been found that the eye movement of APS patients has different degrees of obstacles,and the eye movement assessment has the advantage of non-invasiveness,which has certain auxiliary diagnostic value for APS.Therefore,this article will systematically review the eye movement disorders of APS.
NETL
NSTL
维普
万方数据