Related influencing factors of secondary epilepsy after traumatic skull defect repair
Objective To explore the related influencing factors of secondary epilepsy after traumatic skull defect repair.Methods A total of 88 patients who underwent skull defect repair from January 2017 to December 2021 were selected as the study objects.According to whether secondary epilepsy occurred,the patients were divided into epilepsy group(25 cases)and non-epilepsy group(63 cases).The general data of the two groups were collected,and univariate and multivariate Logistic regression analysis were performed to determine the influencing factors for secondary epilepsy after traumatic skull defect repair.Results There were statistically significant differences in the time from repair surgery to trauma>6 months,preoperative Glasgow Coma Scale(GCS)score,intraoperative suspension,postoperative regular use of anti-epileptic preventive drugs and cerebral gray matter softening lesion between the two groups(P<0.05).Multivariate Logistic regression analysis showed that the time from repair surgery to trauma>6 months,preoperative GCS score,intraoperative suspension,postoperative regular use of anti-epileptic preventive drugs and cerebral gray matter softening lesion were independent influencing factors for secondary epilepsy after traumatic skull defect repair(P<0.05).Conclusion The related influencing factors of secondary epilepsy after traumatic skull defect repair include the time from repair surgery to trauma>6 months,preoperative GCS score,intraoperative suspension,postoperative regular use of anti-epileptic preventive drugs,cerebral gray matter softening lesion;preoperative scientific and reasonable GCS score,regular anti-epileptic treatment and good surgical treatment can effectively reduce the possibility of epilepsy.