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外伤性颅骨缺损修补术后继发癫痫的相关影响因素

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目的 探究外伤性颅骨缺损修补术后继发癫痫的相关影响因素。方法 选取2017年1月至2021年12月收治的 88例接受颅骨缺损修补术的患者为研究对象,根据是否继发癫痫将其分为癫痫组(25 例)和非癫痫组(63例)。收集两组的一般资料并进行单因素、多因素Logistic回归分析,以确定外伤性颅骨缺损修补术后继发癫痫的相关影响因素。结果 两组的修补手术时距外伤时间>6 个月、术前格拉斯哥昏迷量表(GCS)评分、术中悬吊、术后正规使用抗癫痫预防用药、脑灰质软化灶情况比较,差异具有统计学意义(P<0。05)。多因素Logistic回归分析结果显示,修补手术时距外伤时间>6个月、术前GCS评分、术中悬吊、术后正规使用抗癫痫预防用药、脑灰质软化灶均为外伤性颅骨缺损修补术后继发癫痫的独立影响因素(P<0。05)。结论 外伤性颅骨缺损修补术后继发癫痫的相关影响因素包括修补手术时距外伤时间>6 个月、术前GCS评分、术中悬吊、术后正规使用抗癫痫预防用药、脑灰质软化灶;术前科学合理的GCS评分,开展正规抗癫痫治疗、做好手术处理能够有效降低癫痫发生的可能。
Related influencing factors of secondary epilepsy after traumatic skull defect repair
Objective To explore the related influencing factors of secondary epilepsy after traumatic skull defect repair.Methods A total of 88 patients who underwent skull defect repair from January 2017 to December 2021 were selected as the study objects.According to whether secondary epilepsy occurred,the patients were divided into epilepsy group(25 cases)and non-epilepsy group(63 cases).The general data of the two groups were collected,and univariate and multivariate Logistic regression analysis were performed to determine the influencing factors for secondary epilepsy after traumatic skull defect repair.Results There were statistically significant differences in the time from repair surgery to trauma>6 months,preoperative Glasgow Coma Scale(GCS)score,intraoperative suspension,postoperative regular use of anti-epileptic preventive drugs and cerebral gray matter softening lesion between the two groups(P<0.05).Multivariate Logistic regression analysis showed that the time from repair surgery to trauma>6 months,preoperative GCS score,intraoperative suspension,postoperative regular use of anti-epileptic preventive drugs and cerebral gray matter softening lesion were independent influencing factors for secondary epilepsy after traumatic skull defect repair(P<0.05).Conclusion The related influencing factors of secondary epilepsy after traumatic skull defect repair include the time from repair surgery to trauma>6 months,preoperative GCS score,intraoperative suspension,postoperative regular use of anti-epileptic preventive drugs,cerebral gray matter softening lesion;preoperative scientific and reasonable GCS score,regular anti-epileptic treatment and good surgical treatment can effectively reduce the possibility of epilepsy.

traumatic skull defect repairsecondary epilepsyinfluencing factor

朱浩、孙关、许如东、汤伟强、严正军

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射阳县人民医院,江苏 盐城,224300

盐城市第一人民医院,江苏 盐城,224000

外伤性颅骨缺损修补术 继发癫痫 影响因素

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(4)
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