Co-word cluster analysis of research hotspots on the pathogenesis of liver fibrosis in China
Objective To analyze the hot spots in the research field of liver fibrosis pathogenesis in China since 2000,and to provide reference for the development of liver fibrosis related research.Methods China Biology Medicine disc,China National Knowledge Infrastructure,Wanfang database and Weipu database were searched for literatures on liver fibrosis from January 2000 to October 2022.Bicomb software and SPSS were used to analyze the word frequency and cluster analysis of high-frequency keywords.Results Finally,562 articles were included,and 33 keywords with a frequency of more than 5 times were intercepted.The domestic research hotspots on the pathogenesis of liver fibrosis were clustered into 5 clusters.Conclusion The research hotspots of liver fibrosis in China mainly include five major directions,namely,the diagnosis of liver fibrosis,the study of hepatic stellate cells,the study of traditional Chinese medicine for liver fibrosis,the study of the etiology of liver fibrosis and the study of signaling pathways.