Effect of intravascular intervention combined with intravenous thrombolysis on moderate to severe acute cerebral infarction and its influence on cerebral blood flow
Objective To investigate the effect of intravascular intervention combined with intravenous thrombolysis on moderate to severe acute cerebral infarction and its influence on cerebral blood flow.Methods A total of 156 patients with moderate to severe acute cerebral infarction admitted from January 2021 to January 2022 were selected as the research objects,and the patients were divided into control group and observation group according to treatment methods,with 78 cases in each group.The control group was treated with intravenous thrombolysis,and the observation group was treated with intravascular intervention on the basis of the control group.The therapeutic effects of the two groups were compared.Results After operation,the National Institutes of Health Stroke Scale(NIHSS)score,neuron specific enolase(NSE)and brain natriuretic peptide(BNP)levels of the two groups decreased,the Alberta Stroke Program Early CT Score(ASPECT)score,nerve growth factor(NGF)level,maximum systolic blood flow velocity(Vs),minimum diastolic blood flow velocity(Vd)and mean blood flow velocity(Vm)of middle cerebral artery increased,and those in the observation group were better than the control group(P＜0.05).Conclusion Intravascular intervention combined with intravenous thrombolysis in the treatment of patients with moderate to severe acute cerebral infarction can significantly improve the recovery of neurological function,protect brain tissue,improve prognosis,and has a significant therapeutic effect.
intravascular interventionintravenous thrombolysismoderate to severe acute cerebral infarctionneurological function
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