Effect of ultrasonic scalpel combined with bipolar electrocoagulation in the treatment of thyroid nodules
Objective To analyze the feasibility of ultrasonic scalpel combined with bipolar electrocoagulation in thyroid nodules surgery.Methods A total of 50 patients with thyroid nodules who needed surgical treatment from January to December 2021 were selected as the research objects.According to the parity of the admission number,the patients were divided into control group and observation group,with 25 cases in each group.Both groups underwent conventional open ultrasonic scalpel thyroid surgery,the control group was used to silk ligation to stop bleeding,and the observation group was used to bipolar electrocoagulation to stop bleeding.The surgical indexes,incidence of postoperative complications,inflammatory indexes,therapeutic effects and immune function indexes were compared between the two groups.Results The operation time,incision length,postoperative hospitalization time and intraoperative hemostasis time of the observation group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group(P＜0.05).The total incidence of postoperative complications in the observation group was significantly lower than that in the control group(P＜0.05).At 1 d after operation,the levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)in the observation group were lower than those in the control group,and the level of interleukin-10(IL-10)was higher than that in the control group(P＜0.05).There was no significant difference in the total effective rate of treatment between the two groups(P＞0.05).At 3 d after operation,CD4+,CD4+/CD8+and natural killer(NK)cell in the observation group were higher than those in the control group,while CD8+and CD4+CD25+were lower than those in the control group(P＜0.05).Conclusion Ultrasonic scalpel combined with bipolar electrocoagulation in the treatment of thyroid nodules can significantly reduce surgical injury and the incidence of postoperative complications,but it cannot improve the total effective rate of treatment.
万方数据
维普
