Application effect of sentinel lymph node biopsy and axillary lymph node dissection in radical mastectomy for early breast cancer and its influences on postoperative upper limb function recovery and tumor markers
Objective To investigate the application effect of sentinel lymph node biopsy and axillary lymph node dissection in radical mastectomy for early breast cancer and its influences on postoperative upper limb function recovery and tumor markers.Methods Sixty patients undergoing radical mastectomy for early breast cancer from January 2020 to January 2023 were selected and divided into control group(30 cases,axillary lymph node dissection)and observation group(30 cases,sentinel lymph node biopsy)by random number table method.The therapeutic effects of the two groups were compared.Results At 6 months after operation,the upper arm circumference of the observation group was smaller than that of the control group,and the shoulder joint activity and shoulder joint function score were higher than those of the control group(P＜0.05).At 6 months after operation,the levels of carcinoembryonic antigen(CEA),cancer antigen 153(CA153)and tissue polypeptide antigen(TPA)in the two groups were lower than those before operation(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group(P＜0.05).At 6 months after operation,CD3+and CD4+in the observation group were higher than those in the control group,and CD8+was lower than that in the control group(P＜0.05).Conclusion Sentinel lymph node biopsy and axillary lymph node dissection have similar effects on serum tumor markers in patients undergoing radical mastectomy for early breast cancer.However,sentinel lymph node biopsy can help promote postoperative upper limb function recovery,reduce the incidence of complications,and improve immune function.
sentinel lymph node biopsyaxillary lymph node dissectionradical mastectomy for early breast cancerupper limb functiontumor marker
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维普
