Analysis of imaging features of Mikulicz's disease of lacrimal gland
Objective To investigate the CT and MRI manifestations and differential diagnosis value of Mikulicz's disease of lacrimal gland.Methods From May 2018 to August 2022,15 patients with Mikulicz's disease of lacrimal gland confirmed by surgery and pathology were selected,and their CT and MRI imaging characteristics were analyzed.Results All 15 patients had bilateral lacrimal gland involvement.Some patients had unilateral lacrimal gland involvement at first,and then gradually developed into bilateral symmetrical enlargement.Most of the lesions were semi-enclosed around the eyeball(the eyeball was normal in shape and did not deform due to compression),and grew along the long axis of the external rectus muscle;some lesions showed"swallow tail sign"with smooth edges.CT showed equal density,MRI showed slightly lower or equal signal on T1-weighted imaging(T1WI),slightly higher or equal signal on T2-weighted imaging(T2WI),and equal signal on diffusion-weighted imaging(DWI)and apparent diffusion coefficient(ADC).MRI enhancement in 10 cases showed uniform and obvious enhancement,of which one patient had a history of gastric lymphoma and bilateral parotid gland involvement,and the volume of the parotid gland increased slightly and the diffuse signal was abnormal.Conclusion Mikulicz's disease of lacrimal gland is an idiopathic autoimmune disease.Orbital CT and MRI can not only help to determine the extent of involvement of the lesion,but also have a certain significance in judging the nature of the lesion.The diagnosis of Mikulicz's disease requires comprehensive consideration of clinical manifestations,imaging and serological examinations,with pathological results as the final diagnosis basis.
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