Comparison of clinical effects of different linear radiofrequency ablation in the treatment of patients with persistent atrial fibrillation
Objective To compare the clinical effects of different linear radiofrequency ablation in the treatment of patients with persistent atrial fibrillation(AF).Methods A total of 79 patients with persistent AF were selected as the study objects.According to different ablation methods,the patients were divided into intimal surface group[51 cases,circumferential pulmonary vein isolation(CPVI)+ left atrial top line + coronary sinus intimal surface]and 2C3L group(28 cases,CPVI + left atrial top line + mitral isthmus line + tricuspid isthmus line).The operation time,left ventricular ejection fraction(LVEF),left atrial end-systolic diameter(LAD),brain natriuretic peptide(BNP)level and AF recurrence rate were compared between the two groups.Results The operation time of the 2C3L group was longer than that of the intimal surface group(P<0.05).The LVEF in the intimal surface group basically showed a gradual increasing trend with the prolongation of time,while the change was not obvious in the 2C3L group,and the difference was statistically significant between the two groups(P<0.05).At 3 and 6 months after operation,the LAD in the 2C3L group was lower than that in the intimal surface group(P<0.05).There was no significant difference in BNP level between the two groups before operation and at 1,3 and 6 months after operation(P>0.05).At 3 and 6 months after operation,there was no significant difference in AF recurrence rate between the two groups(P>0.05).Conclusion Left atrial top line + coronary sinus intimal surface ablation on the basis of CPVI is more effective in improving postoperative LVEF in patients with persistent AF,while 2C3L procedure can significantly reduce postoperative LAD of patients.
万方数据
维普
