Diagnostic effect of thyroid function test combined with TG-Ab and TPO-Ab levels examination in patients with subclinical hypothyroidism
Objective To analyze the diagnostic effect of thyroid function test combined with anti-thyroglobulin antibodies(TG-Ab)and thyroid peroxidase antibody(TPO-Ab)levels examination in patients with subclinical hypothyroidism.Methods One hundred patients with suspected subclinical hypothyroidism admitted in our hospital from October 2021 to October 2023 were selected as the observation group,and 100 healthy volunteers who went to the hospital for routine physical examination during the same period were selected as the control group.All subjects were tested for thyroid function and TG-Ab and TPO-Ab levels after admission,and the diagnostic efficacy of the two examinations alone and in combination was compared and analyzed.Results There were no significant differences in the levels of free triiodothyronine(FT3)and free thyroxine(FT4)between the two groups(P>0.05);the levels of thyroid-stimulating hormone(TSH),TG-Ab and TPO-Ab in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The diagnostic accuracy and sensitivity of combined detection of TSH,FT3,FT4,TG-Ab and TPO-Ab for subclinical hypothyroidism were higher than those of single detection(P<0.05).Conclusion Thyroid function combined with TG-Ab and TPO-Ab detection in the diagnosis of subclinical hypothyroidism can achieve higher diagnostic efficiency.
万方数据
维普
