Application effect of different doses of remazolam on painless gastroscopy in elderly patients
Objective To investigate the application effect of different doses of remazolam on painless gastroscopy in elderly patients.Methods According to the random lottery method,138 elderly patients who underwent painless gastroscopy from July 2021 to July 2022 were divided into A,B and C three groups,with 46 cases in each group.The group A was given propofol anesthesia,the group B was given 0.1 mg/kg remazolam anesthesia,and the group C was given 0.3 mg/kg remazolam anesthesia.The anesthetic effects of the three groups were compared.Results The changes of vital signs in the group B and the group C were more stable than those in the group A(P＜0.05),but there were no significant differences between the two groups at different times(P＞0.05).The anesthesia onset time,sleep time,recovery time,orientation recovery time and leaving room time of the group C were shorter than those of the group A and the group B,and the success rate of sedation was higher than that of the group A and the group B(P＜0.05).The incidences of adverse reactions in the group B and the group C were significantly lower than those in the group A(P＜0.05).At 10 and 30 min after anesthesia recovery,the Montreal Cognitive Assessment Scale(MoCA)score of the group B and the group C was significantly higher than that of the group A(P＜0.05).Conclusion Compared with propofol,remazolam is more conducive to reducing the incidence of adverse reactions and has little effect on cognitive function.In addition,compared with 0.1 mg/kg remazolam,0.3 mg/kg remazolam is more conducive to improving the success rate of sedation and promoting the recovery of anesthesia.
rimazolampropofolpainless gastroscopyadverse reactioncognitive function
万方数据
维普
