Clinical effect and mechanism analysis of Buyang Tongshuan tablets in the treatment of acute cerebral infarction of Qi deficiency and blood stasis type
Objective To explore the clinical effect and mechanism of Buyang Tongshuan tablets in the treatment of acute cerebral infarction(ACI)with Qi deficiency and blood stasis type.Methods A total of 146 ACI patients with Qi deficiency and blood stasis type were divided into control group and observation group by random number table method,with 73 cases in each group.The control group was treated with routine treatment according to the ACI diagnosis and treatment guidelines,and the observation group was treated with Buyang Tongshuan tablets on the basis of the control group.The therapeutic effects of the two groups were compared.Results After treatment,the scores of TCM syndromes and National Institutes of Health Stroke Scale(NIHSS)in the observation group were lower than those in the control group,and the Barthel Index(BI)score was higher than that in the control group(P＜0.05).The total effective rate of treatment in the observation group was significantly higher than that in the control group(P＜0.05).After treatment,the levels of fibrinogen(Fib)and D-dimer(D-D)in the observation group were lower than those in the control group(P＜0.05).After treatment,the cerebrovascular reserve(CVR)of the observation group was higher than that of the control group,and the arterial resistance index(RI)was lower than that of the control group(P＜0.05).Conclusion Buyang Tongshuan tablets have a significant effect on ACI of Qi deficiency and blood stasis type,it can effectively promote the recovery of neurological function and self-care ability of patients,which may be related to the improvement of fibrinolysis-coagulation function,CVR and blood circulation.
acute cerebral infarctionQi deficiency and blood stasis typeBuyang Tongshuan tablet
万方数据
维普
