Analysis of nosocomial infection characteristics of multi-drug resistant bacteria in intensive care unit from 2019 to 2021
Objective To analyze the nosocomial infection characteristics of multi-drug resistant bacteria in intensive care unit from 2019 to 2021.Methods The clinical data of 2 126 patients admitted in the intensive care unit of our hospital from January 2019 to December 2021 were retrospectively selected.The incidence of nosocomial infection of multi-drug resistant bacteria in intensive care unit from 2019 to 2021,the composition of pathogenic bacteria of nosocomial infection of multi-drug resistant bacteria and the incidence of nosocomial infection of multi-drug resistant bacteria in different parts were analyzed.Results From 2019 to 2021,the nosocomial infection rate of multi-drug resistant bacteria showed a decreasing trend year by year.The nosocomial infection rate of multi-drug resistant bacteria in 2021 was lower than that in 2019,and the difference was statistically significant(P=0.019).From 2019 to 2021,a total of 64 strains were detected,of which Carbapenem-resistant Acinetobacter baumannii accounted for the highest proportion(62.50%)of the pathogenic bacteria in the multi-drug resistant bacteria nosocomial infection.The nosocomial infection of multi-drug resistant bacteria in intensive care unit was mainly ventilator-associated,accounting for 48.44%;the lower respiratory tract was the second,accounting for 32.81%;the proportion of urinary tract,urinary catheter and upper respiratory tract were low,accounting for 7.81%,7.81%and 3.13%respectively.Carbapenem-resistant Acinetobacter baumannii and Carbapenem-resistant Enterobacteriaceae were highly resistant to cefepime,imipenem,meropenem,amikacin and levofloxacin(more than 80%).Carbapenem-resistant Pseudomonas aeruginosa was highly resistant to imipenem.Conclusion Nosocomial infection of multi-drug resistant bacteria in intensive care unit is the difficulty and focus of nosocomial infection control.Targeted prevention and control measures should be taken in the diagnosis and treatment according to the characteristics of nosocomial infection of multi-drug resistant bacteria in intensive care unit.In particular,it is necessary to pay attention to the monitoring and prevention and control of nosocomial infection in intensive care unit of Carbapenem-resistant Acinetobacter baumannii and ventilator-associated patients,and rational use of antibiotics.
intensive care unitmulti-drug resistant bacterianosocomial infectionpathogenic bacteria
万方数据
维普
