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组织瓣环运动位移评价心室肥厚患者左室收缩功能

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目的 探讨组织瓣环运动位移(TMAD)自动追踪技术定量评价心室肥厚患者左室收缩功能的应用价值。方法 纳入60 例心室肥厚患者,原发性高血压亚组30 例,尿毒症亚组 30例,纳入35例健康体检者作为对照组。应用二维斑点追踪技术自动获取心尖四腔心切面、心尖两腔心切面二尖瓣环四个位点TMAD值、左心室整体纵向应变(LVGLS)及左室整体圆周应变(LVGCS),应用Bland-Altman法检验TMAD参数一致性及绘制受试者工作特性(ROC)曲线评价TMAD参数的诊断效能。结果 原发性高血压亚组和尿毒症亚组的收缩压(SBP)、舒张压(DBP)明显高于对照组(P<0。05);尿毒症亚组的心率(HR)高于原发性高血压亚组及对照组(P<0。05)。尿毒症亚组的TMAD参数及应变参数均明显低于对照组(P<0。05)。原发性高血压亚组的LVGLS、T-AP4sep、T-AP4mid%、T-AP2int、T-AP2ant及T-AP2mid%低于对照组(P<0。05)。ROC曲线结果显示,TMAD各参数对心室肥厚患者左室收缩功能降低具有中等预测价值。结论 TMAD可以定量评价心室肥厚患者的左室收缩功能,且可重复性好。
Evaluation of left ventricular systolic function in patients with ventricular hypertrophy by tissue motion annular displacement
Objective To explore the application value of automatic tracking technique of tissue motion annular displacement(TMAD)in quantitative evaluation of left ventricular systolic function in patients with ventricular hypertrophy.Methods A total of 60 patients with ventricular hypertrophy were included,including 30 patients in primary hypertension subgroup and 30 patients in uremia subgroup,and 35 healthy subjects were included as control group.The two-dimensional speckle tracking technique was used to automatically obtain the TMAD values of the four sites of the mitral annulus in the apical four-chamber view and the apical two-chamber view,the left ventricular global longitudinal strain(LVGLS)and the left ventricular global circumferential strain(LVGCS).The Bland-Altman method was used to test the consistency of TMAD parameters and the receiver operating characteristic(ROC)curve was drawn to evaluate the diagnostic efficacy of TMAD parameters.Results The systolic blood pressure(SBP)and diastolic blood pressure(DBP)in the primary hypertension subgroup and the uremia subgroup were significantly higher than those in the control group(P<0.05).The heart rate(HR)of the uremia subgroup was higher than that of the primary hypertension subgroup and the control group(P<0.05).The TMAD parameters and strain parameters of the uremia subgroup were significantly lower than those of the control group(P<0.05).LVGLS,T-AP4sep,T-AP4mid%,T-AP2int,T-AP2ant and T-AP2mid%in the primary hypertension subgroup were lower than those in the control group(P<0.05).ROC curve results showed that TMAD parameters had moderate predictive value for left ventricular systolic function in patients with ventricular hypertrophy.Conclusion TMAD can quantitatively evaluate left ventricular systolic function in patients with ventricular hypertrophy,and has good repeatability.

tissue motion annular displacementventricular hypertrophyuremiaprimary hypertensionleft ventricular systolic functionspeckle tracking technique

贾玄慧、亢春苗、沈亚梅、马盼盼、朱媛

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陕西省人民医院超声诊断中心,陕西 西安,710068

组织瓣环运动位移 心室肥厚 尿毒症 原发性高血压 左室收缩功能 斑点追踪技术

陕西省重点研发计划

2022SF-505

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(10)
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