首页|儿童注意缺陷多动障碍与肥胖的相关性及其潜在机制的研究进展

儿童注意缺陷多动障碍与肥胖的相关性及其潜在机制的研究进展

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注意缺陷多动障碍(ADHD)是学龄期常见的神经发育障碍疾病,影响到儿童生活及学习,成年期的ADHD会有认知及品行障碍。近年来因生活习惯改变及社会压力等问题,ADHD的患病率日益增高,研究发现肥胖会加重ADHD的核心症状,对ADHD儿童的日常生活带来负面影响。越来越多的研究发现肥胖与ADHD之间存在广泛的联系,但目前研究方向是ADHD与肥胖共患病的病理机制,主要集中在影像学、神经生化以及遗传之间。本文旨在全面阐述肥胖影响ADHD的发病及其潜在病理生理机制,以促进ADHD患儿进行多方面医学管理,并对于研发治疗ADHD药物具有重要意义。
Research progress on the correlation between attention deficit hyperactivity disorder and obesity in children and its potential mechanism
Attention deficit hyperactivity disorder(ADHD)is a common neurodevelopmental disorder in school age,which affects children's life and learning.ADHD in adulthood will have cognitive and behavioral disorders.In recent years,the prevalence of ADHD has been increasing due to changes in living habits and social pressure.Studies have found that obesity will aggravate the core symptoms of ADHD and have a negative impact on the daily life of children with ADHD.More and more studies have found that there is a wide relationship between obesity and ADHD,but the current research direction is the pathological mechanism of ADHD and obesity comorbidity,mainly focusing on imaging,neurobiochemistry and genetics.The purpose of this article is to comprehensively elaborate the pathogenesis and potential pathophysiological mechanisms of obesity affecting ADHD,so as to promote multi-faceted medical management of ADHD children,and is of great significance for the development of drugs for the treatment of ADHD.

obesityattention deficit hyperactivity disorderinheritanceimmunitypsychological stressgut-brain axiscircadian rhythm

杨梅、张利华、孙婧

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宜昌市第二人民医院/三峡大学附属第二人民医院,湖北 宜昌,443000

肥胖 注意缺陷多动障碍 遗传 免疫 心理应激 肠-脑轴 昼夜节律

宜昌市科技局科技创新项目(2023)

A23-1-047

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(11)
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