Research progress of reactive oxygen species in renal carcinoma
Reactive oxygen species(ROS)is a single electron reduction product of a class of intracellular oxygen,with highly oxidative.It can participate in various cellular life activities and is closely related to the occurrence,development,and treatment of renal carcinoma.Inducing apoptosis,autophagy,and cycle arrest are currently the conventional mechanism for treating cancer,and ROS is closely related to them in renal carcinoma.Radiation therapy has not been common in the treatment of renal carcinoma,but modulation of ROS in combination with radiation therapy is a new treatment way.This article will review the role of ROS in apoptosis,autophagy,cell cycle arrest,and chemoradiotherapy in renal carcinoma cells,as well as the challenges faced in targeting ROS.
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