首页|精细化管理在儿童化疗药物调配中的应用及对不良事件的影响

精细化管理在儿童化疗药物调配中的应用及对不良事件的影响

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目的 探讨精细化管理在儿童化疗药物调配中的应用,并分析其对不良事件的影响.方法 选取2020年1月至2022年12月医院静脉用药调配中心(PIVAS)的300袋化疗药物、10名PIVAS工作人员及60名患儿监护人作为试验组(精细化管理),另选取2017年1月至2019年12月医院PIVAS的300袋化疗药物、10名PIVAS工作人员及60名患儿监护人作为参照组(常规管理).比较两组的各项工作指标、不良事件发生情况、PIVAS工作人员满意度及患儿监护人满意度.结果 试验组的审方时间、配药所需时间、排药时间及药物库存周转时间均短于参照组(P<0.05).试验组的不良事件总发生率为0.33%,低于参照组的3.00%(P<0.05).试验组PIVAS工作人员的满意度调查问卷各项评分均高于参照组(P<0.05).试验组的患儿监护人满意度为98.33%,高于参照组的88.33%(P<0.05).结论 精细化管理可提升儿童化疗药物调配工作效率,降低不良事件发生风险,提高PIVAS工作人员及患儿监护人的满意度.
Application of refined management in the allocation of children's chemotherapeutic drugs and its influence on adverse events
Objective To explore the application of refined management in the allocation of children's chemotherapy drugs,and to analyze its influence on adverse events.Methods From January 2020 to December 2022,300 bags of chemotherapeutic drugs,10 staffs in pharmacy intravenous admixture services(PIVAS)and 60 guardians of children in the PIVAS of the hospital were selected as experimental group(refined management),and 300 bags of chemotherapeutic drugs,10 PIVAS staffs and 60 guardians of children in the PIVAS of the hospital from January 2017 to December 2019 were selected as reference group(routine management).The work indicators,adverse events,satisfaction of PIVAS staffs and children's guardians were compared between the two groups.Results The prescription review time,dispensing required time,dispensing time and drug inventory turnover time of the experimental group were shorter than those of the reference group(P<0.05).The total incidence of adverse events in the experimental group was 0.33%,which was lower than 3.00%in the reference group(P<0.05).The scores of various items of satisfaction surevey questionnaire of PIVAS staff in the experimental group were higher than those in the reference group(P<0.05).The satisfaction of children's guardians in the experimental group was 98.33%,which was higher than 88.33%in the reference group(P<0.05).Conclusion Refined management can improve the working efficiency of allocation of children's chemotherapy drugs,reduce the risk of adverse events,and improve the satisfaction of PIVAS staffs and children's guardians.

chemotherapeutic drugsrefined managementadverse eventchildrenpharmacy intravenous admixture services

田音、仵利娟

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西北妇女儿童医院药剂科静配中心,陕西西安,710061

眉县人民医院内分泌血液肿瘤科,陕西 宝鸡,722300

化疗药物 精细化管理 不良事件 儿童 静脉用药调配中心

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(12)
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